An infantile traumatic brain injury with a bright tree appearance detected before the late seizure

• Published in: Child's nervous system Vol. 39; no. 1; pp. 285 - 288
• Main Authors: Kaneko, Naoki, Nishizawa, Hideo, Fujimoto, Junichi, Nanao, Taikan, Kimura, Yasuhiro, Owada, Gen
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 2023
• Subjects: Brain Diseases; Brain Injuries, Traumatic; Case Report; Disease Progression; Humans; Infant; Infant, Newborn; Medicine; Medicine & Public Health; Neurosciences; Neurosurgery; Seizures; Trees; Acute encephalopathy with biphasic seizures and late reduced diffusion; Infant; Bright tree appearance; Traumatic brain injury; Subdural hematoma
• ISSN: 0256-7040; 1433-0350
• DOI: 10.1007/s00381-022-05589-2

Indroduction Infantile traumatic brain injury (TBI) rarely follows a biphasic clinical course and exhibits a bright tree appearance (BTA) on magnetic resonance imaging (MRI). This is termed infantile traumatic brain injury with a biphasic clinical course and late reduced diffusion (TBIRD). TBIRD has clinical features similar to those of acute encephalopathy with biphasic seizures and late reduced diffusion (AESD). It remains to be clarified which patients with infantile TBI will develop TBIRD and the prevention and treatment of TBIRD. Case and review We report a case of TBIRD that exhibited BTA 1 day before the late seizure and review 12 cases of TBIRD. All patients developed a subdural hematoma (SDH), were younger than 2 years, and presented with a biphasic phase within 3–6 days. The median interval between BTA and TBI was 5 days. Of the 5 cases examined with MRI before the biphasic phase, only our case was detected with BTA 4 days after TBI. Conclusion Predicting the biphasic clinical course may be possible by examining MRI after TBI in patients under 2 years of age who develop SDH with unconsciousness, seizure, or hemiplegia, and these patients should be strictly followed up for 1 week.