The Unguided Risks in APLA Syndrome Patient Undergoing Tricuspid Valve Replacement- Call for Management Guidelines

• Published in: Journal of the Practice of Cardiovascular Sciences Vol. 11; no. 1; pp. 88 - 92
• Main Authors: Yadav, Mayank, Rajeev, Meera, Gupta, Abhinav
• Format: Journal Article
• Language: English
• Published: India Wolters Kluwer - Medknow 2025; Medknow Publications and Media Pvt. Ltd; Wolters Kluwer Medknow Publications
• Edition: 2
• Subjects: Antibodies; Anticardiolipin antibodies; antiphospholipid antibody syndrome; Antiphospholipid syndrome; Bivalirudin; Blood clot; Cardiac patients; Case Report; Health aspects; Heart diseases; Heart valve replacement; Methods; Mortality; Patient outcomes; right atrial thrombus; Risk factors; Strategic planning (Business); thrombocytopenia; Thrombosis; tricuspid stenosis; Viral antibodies; India; Antiphospholipid antibody syndrome; tricuspid stenosis; thrombocytopenia; right atrial thrombus
• ISSN: 2395-5414; 2454-2830
• DOI: 10.4103/jpcs.jpcs_89_24

Abstract The prevalence of heart valve involvement in antiphospholipid antibody (APLA) syndrome (APLS) is 14.3%. The mortality rate after valve replacement surgery in this group of patients is double that of the normal population. Currently, there are no specific therapeutic guidelines available for the management of patients of APLA syndrome with valvular heart disease. Hence, it is important to establish guidelines for preoperative optimization and perioperative management of these patients undergoing heart valve replacement. Here, we describe the management strategy for tricuspid valve replacement in a young female with secondary APLA syndrome with right atrial thrombus.