Clinicopathological features and expression of four keratins (K10, K14, K17 and K19) in six cases of eruptive vellus hair cysts

Summary Six cases of eruptive vellus hair cysts (EVHC) were evaluated for histopathology and the immunohistochemical profile of Ki‐67 and four keratins (K10, K14, K17 and K19). The pathological hallmark of EVHC was the existence of vellus hair shafts within the cystic cavity, but atypical pathologic...

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Bibliographic Details
Published inClinical and experimental dermatology Vol. 39; no. 4; pp. 496 - 499
Main Authors Shi, G., Zhou, Y., Cai, Y.-X., Li, S.-J., Fan, Y.-M.
Format Journal Article
LanguageEnglish
Published England Blackwell Publishing Ltd 01.06.2014
Oxford University Press
Subjects
Adolescent
Adult
Cysts
Epidermal Cyst - metabolism
Epidermal Cyst - pathology
Female
Hair
Hair Diseases - metabolism
Hair Diseases - pathology
Humans
Keratinocytes - metabolism
Keratins - metabolism
Male
Middle Aged
Skin Diseases - metabolism
Skin Diseases - pathology
Young Adult
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Summary:Summary Six cases of eruptive vellus hair cysts (EVHC) were evaluated for histopathology and the immunohistochemical profile of Ki‐67 and four keratins (K10, K14, K17 and K19). The pathological hallmark of EVHC was the existence of vellus hair shafts within the cystic cavity, but atypical pathological changes included two or three cysts and a foreign‐body granuloma in three cases. Our results demonstrate that atypical pathological changes are not uncommon in EVHC, and indicate that based on keratin expression, it is likely that EVHC is derived from the infrainfundibulum and sebaceous duct.
Bibliography:istex:C38F59A8E1744779D0574A898D6F0205F74546C7
ark:/67375/WNG-4KW2CGH5-K
ArticleID:CED12337
ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:0307-6938
1365-2230
DOI:10.1111/ced.12337