The relationship between chronic obstructive pulmonary disease and transcatheter aortic valve implantation-A systematic review and meta-analysis

• Published in: Catheterization and cardiovascular interventions Vol. 87; no. S1; pp. 570 - 578
• Main Authors: Liao, Yan-Biao, He, Ze-Xia, Zhao, Zhen-Gang, Wei, Xin, Zuo, Zhi-liang, Li, Yi-Jian, Xiong, Tian-Yuan, Xu, Yuan-Ning, Feng, Yuan, Chen, Mao
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.03.2016; Wiley Subscription Services, Inc
• Subjects: Acute Kidney Injury - epidemiology; Aged, 80 and over; aortic stenosis; Aortic Valve Stenosis - diagnosis; Aortic Valve Stenosis - mortality; Aortic Valve Stenosis - therapy; Body Mass Index; Cardiac Catheterization - instrumentation; Cardiac Catheterization - methods; Cardiac Catheterization - mortality; Chi-Square Distribution; chronic obstructive pulmonary disease; Comorbidity; Exercise Test; Exercise Tolerance; Female; Heart Valve Prosthesis; Heart Valve Prosthesis Implantation - instrumentation; Heart Valve Prosthesis Implantation - methods; Heart Valve Prosthesis Implantation - mortality; Humans; Logistic Models; Lung - physiopathology; Male; Multivariate Analysis; Odds Ratio; Prevalence; Pulmonary Disease, Chronic Obstructive - diagnosis; Pulmonary Disease, Chronic Obstructive - epidemiology; Pulmonary Disease, Chronic Obstructive - mortality; Pulmonary Disease, Chronic Obstructive - physiopathology; Renal Insufficiency, Chronic - epidemiology; Risk Factors; Severity of Illness Index; Time Factors; transcatheter aortic valve; Treatment Outcome; Walking; transcatheter aortic valve; aortic stenosis; chronic obstructive pulmonary disease
• ISSN: 1522-1946; 1522-726X
• DOI: 10.1002/ccd.26443

Objective The present study was performed to investigate the relationship between chronic obstructive pulmonary disease (COPD) and transcatheter aortic valve implantation (TAVI). Background: Controversies regarding the relationship between COPD and TAVI have intensified. Methods: A literature review of the PubMed online database was performed, and articles published between January 1, 2002 and March 20, 2015 were analyzed. Random‐effect and fixed‐effect models were used, depending on the between‐study heterogeneity. Results: A total of 28 studies, involving 51,530 patients, were identified in our review. The burden of COPD ranged from 12.5% to 43.4%, and COPD negatively impacted both short‐term and long‐term all‐cause survival (30 days: odds ratio [OR], 1.43, 95% CI, 1.14–1.79; >2 years: hazard ratio [HR], 1.34, 95% CI, 1.12–1.61). COPD was also associated with increased short‐term and mid‐term cardiac‐cause mortality (30 days: OR, 1.29, 95% CI, 1.02–1.64; 1 year: HR: 1.09, 1.02–1.17). Moreover, COPD (OR, 1.97, 95% CI, 1.29–3.0) predicted post‐TAVI acute kidney disease. Importantly, chronic kidney disease (CKD) (HR, 1.2, 95% CI, 1.1–1.32) and the distance of the 6 minute walk test (6MWT) (HR, 1.16, 1.06–1.27) predicted TAVI futility in patients with COPD. Conclusion: COPD is common among patients undergoing TAVI, and COPD impacts both short‐ and long‐term survival. COPD patients, who had a lower BMI, shorter distance of 6MWT and CKD, were at higher risk for TAVI futility. © 2016 Wiley Periodicals, Inc.