Paraneoplastic Hyperaldosteronism Associated with Non-Hodgkin's Lymphoma

To the Editor: Hyperaldosteronism is the cause of about 0.5 to 2 percent of all cases of hypertension. Aldosterone-producing adenomas account for approximately 60 percent of the cases of hyperaldosteronism, and bilateral adrenal hyperplasia accounts for the remaining 40 percent. Its occurrence as a...

Full description

Saved in:
Bibliographic Details
Published inThe New England journal of medicine Vol. 344; no. 20; pp. 1558 - 1559
Main Authors Mulatero, Paolo, Rabbia, Franco, Veglio, Franco
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 17.05.2001
Subjects
Aldosterone - blood
Cytochrome P-450 CYP11B2 - genetics
Fatal Outcome
Humans
Hyperaldosteronism - etiology
Hypertension - etiology
Lymph Nodes - metabolism
Lymphoma, Non-Hodgkin - complications
Male
Middle Aged
Paraneoplastic Syndromes - complications
Renin - blood
RNA, Messenger - metabolism
Online AccessGet full text

Cover

More Information
Summary:To the Editor: Hyperaldosteronism is the cause of about 0.5 to 2 percent of all cases of hypertension. Aldosterone-producing adenomas account for approximately 60 percent of the cases of hyperaldosteronism, and bilateral adrenal hyperplasia accounts for the remaining 40 percent. Its occurrence as a paraneoplastic syndrome is very rare. We describe a patient with hyperaldosteronism in whom the excess aldosterone was caused by a non-Hodgkin's lymphoma. The patient was a 57-year-old man who presented with easy fatigability and headache. He had had hypertension for two months and was receiving enalapril therapy. His blood pressure was 215/140 mm Hg. Physical examination . . .
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJM200105173442017