“Super-Spreaders” and Person-to-Person Transmission of Andes Virus in Argentina

In late 2018, Andes virus was identified as the cause of an outbreak of hantavirus pulmonary syndrome in Argentina. This outbreak was associated with 34 confirmed infections and 11 deaths. A detailed investigation identified person-to-person transmission that was driven by three symptomatic persons.

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Bibliographic Details
Published inThe New England journal of medicine Vol. 383; no. 23; pp. 2230 - 2241
Main Authors Martínez, Valeria P, Di Paola, Nicholas, Alonso, Daniel O, Pérez-Sautu, Unai, Bellomo, Carla M, Iglesias, Ayelén A, Coelho, Rocio M, López, Beatriz, Periolo, Natalia, Larson, Peter A, Nagle, Elyse R, Chitty, Joseph A, Pratt, Catherine B, Díaz, Jorge, Cisterna, Daniel, Campos, Josefina, Sharma, Heema, Dighero-Kemp, Bonnie, Biondo, Emiliano, Lewis, Lorena, Anselmo, Constanza, Olivera, Camila P, Pontoriero, Fernanda, Lavarra, Enzo, Kuhn, Jens H, Strella, Teresa, Edelstein, Alexis, Burgos, Miriam I, Kaler, Mario, Rubinstein, Adolfo, Kugelman, Jeffrey R, Sanchez-Lockhart, Mariano, Perandones, Claudia, Palacios, Gustavo
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 03.12.2020
Subjects
Adolescent
Adult
Animals
Argentina - epidemiology
Blood Chemical Analysis
Carrier State
Contact tracing
Coronaviruses
Cytokines
Disease Outbreaks
Disease transmission
Epidemics
Epidemiology
Female
Genomes
Hantavirus
Hantavirus - genetics
Hantavirus pulmonary syndrome
Hantavirus Pulmonary Syndrome - epidemiology
Hantavirus Pulmonary Syndrome - mortality
Hantavirus Pulmonary Syndrome - transmission
Hantavirus Pulmonary Syndrome - virology
Haplotypes
High-Throughput Nucleotide Sequencing
Humans
Infections
Laboratories
Male
Middle Aged
Next-generation sequencing
Outbreaks
Patients
Phylogenetics
Phylogeny
Public health
Rodentia
Severe acute respiratory syndrome coronavirus 2
Viral Load
Young Adult
Zoonoses
Argentina
Chile
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Summary:In late 2018, Andes virus was identified as the cause of an outbreak of hantavirus pulmonary syndrome in Argentina. This outbreak was associated with 34 confirmed infections and 11 deaths. A detailed investigation identified person-to-person transmission that was driven by three symptomatic persons.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa2009040