Interim Guidelines for the Evaluation and Testing of Infants with Possible Congenital Zika Virus Infection — United States, 2016

• Published in: MMWR. Morbidity and mortality weekly report Vol. 65; no. 3; pp. 63 - 67
• Main Authors: Staples, J. Erin, Dziuban, Eric J., Fischer, Marc, Cragan, Janet D., Rasmussen, Sonja A., Cannon, Michael J., Frey, Meghan T., Renquist, Christina M., Lanciotti, Robert S., Muñoz, Jorge L., Powers, Ann M., Honein, Margaret A., Moore, Cynthia A.
• Format: Journal Article
• Language: English
• Published: United States Center for Surveillance, Epidemiology, and Laboratory Services, Centers for Disease Control and Prevention (CDC), U.S. Department of Health and Human Services 29.01.2016
• Subjects: Centers for Disease Control and Prevention (U.S.); Female; Humans; Infant; Practice Guidelines as Topic; Pregnancy; Pregnancy Complications, Infectious; United States; Zika virus; Zika Virus Infection - congenital; Zika Virus Infection - diagnosis; United States
• ISSN: 0149-2195; 1545-861X; 1545-861X
• DOI: 10.15585/mmwr.mm6503e3

CDC has developed interim guidelines for health care providers in the United States who are caring for infants born to mothers who traveled to or resided in an area with Zika virus transmission during pregnancy. These guidelines include recommendations for the testing and management of these infants. Guidance is subject to change as more information becomes available; the latest information, including answers to commonly asked questions, can be found online (http://www.cdc.gov/zika). Pediatric health care providers should work closely with obstetric providers to identify infants whose mothers were potentially infected with Zika virus during pregnancy (based on travel to or residence in an area with Zika virus transmission [http://wwwnc.cdc.gov/travel/notices]), and review fetal ultrasounds and maternal testing for Zika virus infection (see Interim Guidelines for Pregnant Women During a Zika Virus Outbreak*) (1). Zika virus testing is recommended for 1) infants with microcephaly or intracranial calcifications born to women who traveled to or resided in an area with Zika virus transmission while pregnant; or 2) infants born to mothers with positive or inconclusive test results for Zika virus infection. For infants with laboratory evidence of a possible congenital Zika virus infection, additional clinical evaluation and follow-up is recommended. Health care providers should contact their state or territorial health department to facilitate testing. As an arboviral disease, Zika virus disease is a nationally notifiable condition.