Flexible Doppler ultrasound device for the monitoring of blood flow velocity

• Published in: Science advances Vol. 7; no. 44; p. eabi9283
• Main Authors: Wang, Fengle, Jin, Peng, Feng, Yunlu, Fu, Ji, Wang, Peng, Liu, Xin, Zhang, Yingchao, Ma, Yinji, Yang, Yingyun, Yang, Aiming, Feng, Xue
• Format: Journal Article
• Language: English
• Published: United States American Association for the Advancement of Science 29.10.2021
• Subjects: Applied Sciences and Engineering; Engineering; Physical and Materials Sciences; SciAdv r-articles
• ISSN: 2375-2548; 2375-2548
• DOI: 10.1126/sciadv.abi9283

Flexible, angled transducer arrays offer direct blood flow measurements. Thrombosis and restenosis after vascular reconstruction procedures may cause complications such as stroke, but a clinical means to continuously monitor vascular conditions is lacking. Conventional ultrasound probes are rigid, particularly for postoperative patients with fragile skin. Techniques based on photoplethysmography or thermal analysis provide only relative changes in flow volume and have a shallow detection depth. Here, we introduce a flexible Doppler ultrasound device for the continuous monitoring of the absolute velocity of blood flow in deeply embedded arteries based on the Doppler effect. The device is thin (1 mm), lightweight (0.75 g), and skin conforming. When the dual-beam Doppler method is used, the influence of the Doppler angle on the velocity measurement is avoided. Experimental studies on ultrasound phantoms and human subjects demonstrate accurate measurement of the flow velocity. The wearable Doppler device has the potential to enhance the quality of care of patients after reconstruction surgery.