Early Rhythm-Control Therapy in Patients with Atrial Fibrillation

In this multicenter, randomized trial comparing early rhythm control with usual care in patients with early atrial fibrillation and cardiovascular conditions, early rhythm control reduced the rate of death from cardiovascular causes and cardiovascular complications and did not affect the number of n...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 383; no. 14; pp. 1305 - 1316
Main Authors Kirchhof, Paulus, Camm, A. John, Goette, Andreas, Brandes, Axel, Eckardt, Lars, Elvan, Arif, Fetsch, Thomas, van Gelder, Isabelle C, Haase, Doreen, Haegeli, Laurent M, Hamann, Frank, Heidbüchel, Hein, Hindricks, Gerhard, Kautzner, Josef, Kuck, Karl-Heinz, Mont, Lluis, Ng, G. Andre, Rekosz, Jerzy, Schoen, Norbert, Schotten, Ulrich, Suling, Anna, Taggeselle, Jens, Themistoclakis, Sakis, Vettorazzi, Eik, Vardas, Panos, Wegscheider, Karl, Willems, Stephan, Crijns, Harry J.G.M, Breithardt, Günter
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 01.10.2020
Subjects
Ablation
Acute Coronary Syndrome - epidemiology
Acute coronary syndromes
Aged
Anti-Arrhythmia Agents - adverse effects
Anti-Arrhythmia Agents - therapeutic use
Arrhythmia
Atrial Fibrillation - complications
Atrial Fibrillation - drug therapy
Atrial Fibrillation - surgery
Cardiac arrhythmia
Cardiovascular disease
Cardiovascular diseases
Cardiovascular Diseases - mortality
Cardiovascular Diseases - prevention & control
Catheter Ablation
Congestive heart failure
Design
Electrocardiography
Female
Fibrillation
Follow-Up Studies
Heart failure
Heart Failure - epidemiology
Hospitalization - statistics & numerical data
Humans
Incidence
Length of Stay
Male
Patients
Quality of life
Questionnaires
Recruitment
Research centers
Risk
Secondary Prevention
Single-Blind Method
Statistical analysis
Stroke
Ventricle
Ventricular Function, Left - drug effects
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Summary:In this multicenter, randomized trial comparing early rhythm control with usual care in patients with early atrial fibrillation and cardiovascular conditions, early rhythm control reduced the rate of death from cardiovascular causes and cardiovascular complications and did not affect the number of nights in the hospital.
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ISSN:0028-4793
1533-4406
1533-4406
DOI:10.1056/NEJMoa2019422