Quartan malarial nephrotic syndrome in children

The nephrotic syndrome is characterized by profuse albuminuria, hypoalbuminemia, generalized edema, and usually hyperlipidemia [1]. The syndrome occurs world wide and may occur at any age, but it has a predeliction for the early years of life [2, 3]. Many etiologic factors have been incriminated, an...

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Bibliographic Details
Published inKidney international Vol. 16; no. 1; pp. 64 - 74
Main Authors Hendrickse, R.G., Adeniyi, Adeoye
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.07.1979
Subjects
Antigen-Antibody Complex
Antimalarials - therapeutic use
Child
Child, Preschool
Complement C3
Humans
Immunoglobulin G
Infant
Kidney Glomerulus - pathology
Kidney Glomerulus - ultrastructure
Malaria - immunology
Malaria - pathology
Nephrotic Syndrome - etiology
Nephrotic Syndrome - parasitology
Nephrotic Syndrome - pathology
Nigeria
North America
Plasmodium malariae - immunology
Prognosis
Retrospective Studies
Nigeria
North America
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Summary:The nephrotic syndrome is characterized by profuse albuminuria, hypoalbuminemia, generalized edema, and usually hyperlipidemia [1]. The syndrome occurs world wide and may occur at any age, but it has a predeliction for the early years of life [2, 3]. Many etiologic factors have been incriminated, and the renal pathology is extremely variable, but in most cases seen in childhood, in temperate climates, no specific cause can be identified, and renal histology by light microscopy is unremarkable. Such cases are referred to as “idiopathic” or “minimal change” nephrotic syndrome and are representative of the vast majority of patients who constitute the basis for the considerable world literature on the nephrotic syndrome in childhood [4].
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0085-2538
1523-1755
DOI:10.1038/ki.1979.103