Retrospective analysis of the key molecules involved in the green synthesis of nanoparticles
Emerging nanotechnology leads to success in synthesizing and applying nanoparticles (NPs) using the green-chemistry approach. NPs synthesized using naturally derived materials are a potential alternative to chemical and physical methods because they are simple, cost-effective, eco-friendly, and lowe...
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| Published in | Nanoscale Vol. 14; no. 4; pp. 14824 - 14857 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Cambridge
Royal Society of Chemistry
21.10.2022
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| Subjects | |
| Online Access | Get full text |
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| Summary: | Emerging nanotechnology leads to success in synthesizing and applying nanoparticles (NPs) using the green-chemistry approach. NPs synthesized using naturally derived materials are a potential alternative to chemical and physical methods because they are simple, cost-effective, eco-friendly, and lower the possibility of hazardous residues being released into the environment. Furthermore, NPs synthesized using the green synthesis approach are stable and biocompatible. However, because natural extracts contain a diverse spectrum of bioactive components, it is difficult to pinpoint the specific component involved in NP formation. Furthermore, the bioactive component contained in the extract changes based on a number of environmental factors; therefore, several studies began with the synthesis of NPs using a pure compound isolated from diverse natural sources. Hence, the present review paper makes an effort to retrospectively analyze the key compounds of the extracts which are responsible for the synthesis of the NPs. The analysis was carried out based on the physicochemical characteristics and biological activities of NPs synthesized from either the extract or the pure compounds. These pure-compound-based NPs were studied for their antimicrobial, antibiofilm, anti-inflammatory, anticancer, and antioxidant properties. In addition, the present review also describes progress in the study of pure compound-based numerous biological activities and the underlying mechanisms of action.
Emerging nanotechnology leads to success in synthesizing and applying nanoparticles (NPs) using the green-chemistry approach. |
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| Bibliography: | https://doi.org/10.1039/d2nr03632k Fazlurrahman Khan obtained his PhD in Microbiology from Jawaharlal Nehru University and M.Sc. in Biotechnology from Madurai Kamaraj University in India. He is a Research Professor at the Research Center for Marine Integrated Bionics Technology, Pukyong National University in South Korea. His most recent research focuses on (1) isolating and characterizing natural molecules that may inhibit the biofilm and virulence properties of both fungal and bacterial pathogens, (2) the chemical synthesis of molecules with antimicrobial potential, (3) polymeric and metallic nanoparticle synthesis for application as potential antimicrobial and antibiofilm drugs, and (4) investigating the molecular mechanisms of bacterial and fungal pathogen interactions in polymicrobial biofilms. Electronic supplementary information (ESI) available. See DOI Young-Mog Kim is Professor in the Department of Food Science and Technology, Pukyong National University, South Korea. He received his PhD in Pharmacy from Okayama University in Japan. After receiving his PhD, he became an assistant professor at Pukyong National University in South Korea. He is currently a professor and the Dean of Student Affairs at Pukyong National University. His research focuses on the treatment of microbial pathogens using both naturally derived and chemically synthesized compounds. He works with natural and synthetic compounds, nanoformulation, and combination therapies to control the virulence and biofilm formation ability of microbial pathogens. In addition, he focuses on natural methods of managing the microbial contamination of various food products. He is also engaged in the physiochemical and biochemical analyses of different food materials. ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
| ISSN: | 2040-3364 2040-3372 2040-3372 |
| DOI: | 10.1039/d2nr03632k |