Formation of multilamellar vesicles (‘onions’) in peptide based surfactant

Concentration dependent morphological characteristics of a novel dipeptide derivative Lys-Asp-Lauryl.HBr ( 1) has been presented. Evidence for “onion” like vesicle formation at higher concentration (>8.2×10 −3 M) of peptide ( 1) in aqueous medium was obtained from conductance and 90° light scatte...

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Published inBioorganic & medicinal chemistry letters Vol. 10; no. 14; pp. 1547 - 1550
Main Authors Jayakumar, R, Murugesan, M, Ahmed, M.Rafiuddin
Format Journal Article
LanguageEnglish
Published Oxford Elsevier Ltd 17.07.2000
Elsevier
Subjects
Chemistry
Colloidal state and disperse state
Cryoelectron Microscopy
Dipeptides - chemical synthesis
Dipeptides - chemistry
Exact sciences and technology
General and physical chemistry
Lipoproteins - chemical synthesis
Lipoproteins - chemistry
Membranes
Molecular Conformation
Molecular Structure
Solutions
Surface-Active Agents - chemistry
Water
Vesicle
Self assembly
Multilayer
Peptides
Electrical properties
Light scattering
Conductivity
Cryogenic temperature
Transmission electron microscopy
Molecular assembly
Morphology
Optical properties
Dipeptides
Hydrobromides
Micellization
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Summary:Concentration dependent morphological characteristics of a novel dipeptide derivative Lys-Asp-Lauryl.HBr ( 1) has been presented. Evidence for “onion” like vesicle formation at higher concentration (>8.2×10 −3 M) of peptide ( 1) in aqueous medium was obtained from conductance and 90° light scattering measurements, and cryo-transmission electron microscopic studies.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0960-894X
1464-3405
DOI:10.1016/S0960-894X(00)00289-4