Fatigue, Participation and Quality of Life in Adolescents and Young Adults with Acquired Brain Injury in an Outpatient Rehabilitation Cohort

• Published in: Developmental neurorehabilitation Vol. 23; no. 5; pp. 328 - 335
• Main Authors: van Markus-Doornbosch, Frederike, van der Holst, Menno, de Kloet, Arend J., Vliet Vlieland, Thea P. M., Meesters, Jorit J. L.
• Format: Journal Article
• Language: English
• Published: Taylor & Francis 03.07.2020
• Subjects: acquired brain injury; adolescents and young adults; Fatigue; participation; quality of life
• ISSN: 1751-8423; 1751-8431
• DOI: 10.1080/17518423.2019.1692948

To study the association between fatigue and participation and QoL after acquired brain injury (ABI) in adolescents and young adults (AYAs). Cross-sectional study with AYAs aged 14-25 years, diagnosed with ABI. The PedsQL™ Multidimensional Fatigue Scale, Child & Adolescent Scale of Participation, and PedsQL™4.0 Generic Core Scales were administered. Sixty-four AYAs participated in the study, 47 with traumatic brain injury (TBI). Median age at admission was 17.6 yrs, 0.8 yrs since injury. High levels of fatigue (median 44.4 (IQR 34.7, 59.7)), limited participation (median 82.5 (IQR 68.8, 92.3)), and diminished QoL (median 63.0 (IQR 47.8, 78.3)) were reported. More fatigue was significantly associated with more participation restrictions (β 0.64, 95%CI 0.44, 0.85) and diminished QoL (β 0.87, 95%CI 0.72, 1.02). AYAs with ABI reported high levels of fatigue, limited participation and diminished quality of life with a significant association between fatigue and both participation and QoL. Targeting fatigue in rehabilitation treatment could potentially improve participation and QoL.