Impact of 24 weeks of supervised endurance versus resistance exercise training on left ventricular mechanics in healthy untrained humans

• Published in: Journal of applied physiology (1985) Vol. 126; no. 4; pp. 1095 - 1102
• Main Authors: Oxborough, David L, Spence, Angela, George, Keith P, Van Oorschot, Frederieke, Thijssen, Dick H T, Green, Daniel J
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.04.2019
• Subjects: Cardiovascular diseases; Fitness training programs; Health risks; Heart; Image acquisition; Mechanics; Mechanics (physics); Physical training; Resistance training; Risk analysis; Risk factors; Rotation; Strain; Strength training; Training; Ventricle; speckle tracking; cardiac mechanics; imaging; echocardiography
• ISSN: 8750-7587; 1522-1601
• DOI: 10.1152/japplphysiol.00405.2018

In addition to the well-known cardiac structural adaptation to exercise training, little work has examined changes in left ventricle (LV) mechanics. With new regional and global indexes available we sought to determine the effect of 24-wk endurance versus resistance training on LV mechanics. Twenty-three male subjects were randomly allocated to a 24-wk endurance or resistance training program. Pre- and posttraining two-dimensional echocardiographic images were acquired. Global LV mechanics [strain (ε)] were recorded in longitudinal, circumferential, and radial planes. Rotation was assessed at apical and basal levels. In addition, longitudinal ε-volume loops, across the cardiac cycle, were constructed from simultaneous LV ε (longitudinal and transverse strain) and volume measurements across the cardiac cycle as a novel measure of LV mechanics. Marginal differences in ε and rotation data were found between groups. After training, we found no change in global peak ε data. Peak basal rotation significantly increased after training, with changes in the endurance group (-2.2 ± 1.9° to -4.5 ± 3.3°) and the resistance group (-2.9 ± 3.0° to -3.4 ± 2.9°). LV ε-volume loops revealed a modest rightward shift in both groups. Although most global and regional indexes of LV mechanics were not significantly altered, 24 wk of intense supervised exercise training increased basal rotation. Further studies that assess LV mechanics in larger cohorts of subjects and those with cardiovascular disease and risk factors may reveal important training impacts. This study builds on previous work by our group and presents a comprehensive assessment of cardiac mechanics after dichotomous exercise training programs. We highlight novel findings in addition to the inclusion of strain-volume loops, which shed light on subtle differences in longitudinal and transverse contribution to volume change throughout the cardiac cycle. Our findings suggest that training has an impact on basal rotation and possibly strain-volume loops.