The use of human immunodeficiency virus postexposure prophylaxis after successful artificial insemination

A case is reported of a woman who was exposed to human immunodeficiency virus through self-insemination. She was artificially inseminated with fresh semen obtained from a gay man in whom HIV seroconversion was taking place. Postexposure prophylaxis with antiretrovirals was initiated 10 days later, a...

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Published inAmerican journal of obstetrics and gynecology Vol. 181; no. 3; pp. 760 - 761
Main Authors Bloch, Mark, Carr, Andrew, Vasak, Eva, Cunningham, Phillip, Smith, Don
Format Journal Article
LanguageEnglish
Published Philadelphia, PA Mosby, Inc 01.09.1999
Elsevier
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Abstract A case is reported of a woman who was exposed to human immunodeficiency virus through self-insemination. She was artificially inseminated with fresh semen obtained from a gay man in whom HIV seroconversion was taking place. Postexposure prophylaxis with antiretrovirals was initiated 10 days later, and despite successful conception, HIV infection was not established. A healthy male infant was subsequently delivered with no obvious toxicity related to medication. (Am J Obstet Gynecol 1999;181:760-1.)
AbstractList A case is reported of a woman who was exposed to human immunodeficiency virus through self-insemination. She was artificially inseminated with fresh semen obtained from a gay man in whom HIV seroconversion was taking place. Postexposure prophylaxis with antiretrovirals was initiated 10 days later, and despite successful conception, HIV infection was not established. A healthy male infant was subsequently delivered with no obvious toxicity related to medication. (Am J Obstet Gynecol 1999;181:760-1.)
A case is reported of a woman who was exposed to human immunodeficiency virus through self-insemination. She was artificially inseminated with fresh semen obtained from a gay man in whom HIV seroconversion was taking place. Postexposure prophylaxis with antiretrovirals was initiated 10 days later, and despite successful conception, HIV infection was not established. A healthy male infant was subsequently delivered with no obvious toxicity related to medication.
Author Carr, Andrew
Smith, Don
Bloch, Mark
Vasak, Eva
Cunningham, Phillip
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Cites_doi 10.1016/S0029-7844(98)00040-4
10.1016/S0140-6736(85)90585-9
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Issue 3
Keywords artificial insemination
Human immunodeficiency virus
antiretrovirals
prophylaxis
Human
Immunopathology
Chemoprophylaxis
Semen
Treatment efficiency
AIDS
Immune deficiency
Infection
Pregnancy
Prevention
Donor
Viral disease
Artificial insemination
Antiviral
Language English
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PublicationTitle American journal of obstetrics and gynecology
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References Stewart, Cunningham, Driscoll (bib2) 1985; 2
(bib3) 1996; 45
Wortley, Hammett, Fleming (bib1) 1998; 91
Wortley (10.1016/S0002-9378(99)70529-6_bib1) 1998; 91
Stewart (10.1016/S0002-9378(99)70529-6_bib2) 1985; 2
(10.1016/S0002-9378(99)70529-6_bib3) 1996; 45
References_xml – volume: 2
  start-page: 581
  year: 1985
  end-page: 585
  ident: bib2
  article-title: Transmission of human T-cell lymphotropic virus type III (HTLV-III) by artificial insemination by donor
  publication-title: Lancet
  contributor:
    fullname: Driscoll
– volume: 91
  start-page: 515
  year: 1998
  end-page: 518
  ident: bib1
  article-title: Donor insemination and human immunodeficiency virus transmission
  publication-title: Obstet Gynecol
  contributor:
    fullname: Fleming
– volume: 45
  start-page: 468
  year: 1996
  end-page: 480
  ident: bib3
  publication-title: Update: provisional Public Health Service recommendations for chemoprophylaxis after occupational exposure to HIV
– volume: 91
  start-page: 515
  year: 1998
  ident: 10.1016/S0002-9378(99)70529-6_bib1
  article-title: Donor insemination and human immunodeficiency virus transmission
  publication-title: Obstet Gynecol
  doi: 10.1016/S0029-7844(98)00040-4
  contributor:
    fullname: Wortley
– volume: 2
  start-page: 581
  year: 1985
  ident: 10.1016/S0002-9378(99)70529-6_bib2
  article-title: Transmission of human T-cell lymphotropic virus type III (HTLV-III) by artificial insemination by donor
  publication-title: Lancet
  doi: 10.1016/S0140-6736(85)90585-9
  contributor:
    fullname: Stewart
– volume: 45
  start-page: 468
  year: 1996
  ident: 10.1016/S0002-9378(99)70529-6_bib3
  publication-title: MMWR Morb Mortal Wkly Rep
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SubjectTerms Adult
Antibiotics. Antiinfectious agents. Antiparasitic agents
antiretrovirals
Antiviral agents
Antiviral Agents - therapeutic use
artificial insemination
Biological and medical sciences
Birth control
Female
Gynecology. Andrology. Obstetrics
HIV Infections - prevention & control
HIV Infections - transmission
HIV Seropositivity
Human immunodeficiency virus
Humans
Indinavir - therapeutic use
Insemination, Artificial, Heterologous
Lamivudine - therapeutic use
Male
Medical sciences
Pharmacology. Drug treatments
Pregnancy
prophylaxis
Sterility. Assisted procreation
Tissue Donors
Tropical medicine
Zidovudine - therapeutic use
Title The use of human immunodeficiency virus postexposure prophylaxis after successful artificial insemination
URI https://dx.doi.org/10.1016/S0002-9378(99)70529-6
https://www.ncbi.nlm.nih.gov/pubmed/10486500
Volume 181
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