The use of human immunodeficiency virus postexposure prophylaxis after successful artificial insemination

• Published in: American journal of obstetrics and gynecology Vol. 181; no. 3; pp. 760 - 761
• Main Authors: Bloch, Mark, Carr, Andrew, Vasak, Eva, Cunningham, Phillip, Smith, Don
• Format: Journal Article
• Language: English
• Published: Philadelphia, PA Mosby, Inc 01.09.1999; Elsevier
• Subjects: Adult; Antibiotics. Antiinfectious agents. Antiparasitic agents; antiretrovirals; Antiviral agents; Antiviral Agents - therapeutic use; artificial insemination; Biological and medical sciences; Birth control; Female; Gynecology. Andrology. Obstetrics; HIV Infections - prevention & control; HIV Infections - transmission; HIV Seropositivity; Human immunodeficiency virus; Humans; Indinavir - therapeutic use; Insemination, Artificial, Heterologous; Lamivudine - therapeutic use; Male; Medical sciences; Pharmacology. Drug treatments; Pregnancy; prophylaxis; Sterility. Assisted procreation; Tissue Donors; Tropical medicine; Zidovudine - therapeutic use; Australia; Oceania; artificial insemination; Human immunodeficiency virus; antiretrovirals; prophylaxis; Human; Immunopathology; Chemoprophylaxis; Semen; Treatment efficiency; AIDS; Immune deficiency; Infection; Pregnancy; Prevention; Donor; Viral disease; Artificial insemination; Antiviral
• ISSN: 0002-9378; 1097-6868
• DOI: 10.1016/S0002-9378(99)70529-6

A case is reported of a woman who was exposed to human immunodeficiency virus through self-insemination. She was artificially inseminated with fresh semen obtained from a gay man in whom HIV seroconversion was taking place. Postexposure prophylaxis with antiretrovirals was initiated 10 days later, and despite successful conception, HIV infection was not established. A healthy male infant was subsequently delivered with no obvious toxicity related to medication. (Am J Obstet Gynecol 1999;181:760-1.)