Five-Year Outcomes after On-Pump and Off-Pump Coronary-Artery Bypass

A total of 2203 patients at 18 medical centers were randomly assigned to undergo on-pump or off-pump CABG. Mortality at 5 years was significantly lower with on-pump CABG than with off-pump CABG. No secondary outcomes indicated a benefit of off-pump surgery.

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Bibliographic Details
Published inThe New England journal of medicine Vol. 377; no. 7; pp. 623 - 632
Main Authors Shroyer, A. Laurie, Hattler, Brack, Wagner, Todd H, Collins, Joseph F, Baltz, Janet H, Quin, Jacquelyn A, Almassi, G. Hossein, Kozora, Elizabeth, Bakaeen, Faisal, Cleveland, Joseph C, Bishawi, Muath, Grover, Frederick L
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 17.08.2017
Subjects
Aged
Cardiovascular Diseases - epidemiology
Cardiovascular Diseases - etiology
Clinical outcomes
Confounding Factors, Epidemiologic
Coronary artery
Coronary Artery Bypass - adverse effects
Coronary Artery Bypass - methods
Coronary Artery Bypass - mortality
Coronary Artery Bypass, Off-Pump - adverse effects
Coronary Artery Bypass, Off-Pump - mortality
Coronary vessels
Death
Disease-Free Survival
Female
Follow-Up Studies
Heart attacks
Heart diseases
Heart rate
Heart surgery
Humans
Kaplan-Meier Estimate
Male
Middle Aged
Mortality
Myocardial infarction
Patients
Survival
Veterans
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Summary:A total of 2203 patients at 18 medical centers were randomly assigned to undergo on-pump or off-pump CABG. Mortality at 5 years was significantly lower with on-pump CABG than with off-pump CABG. No secondary outcomes indicated a benefit of off-pump surgery.
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ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa1614341