Twin-to-twin transfusion syndrome: treatment by amniodrainage and septostomy

• Published in: European journal of obstetrics & gynecology and reproductive biology Vol. 92; no. 1; pp. 141 - 144
• Main Authors: Hubinont, Corinne, Bernard, Pierre, Pirot, Nicolas, Biard, Jean-Marc, Donnez, Jacques
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Shannon Elsevier Ireland Ltd 01.09.2000; Elsevier
• Subjects: Amniodrainage; Amniotic Fluid; Biological and medical sciences; Diseases of mother, fetus and pregnancy; Drainage; Female; Fetal outcome; Fetofetal Transfusion - mortality; Fetofetal Transfusion - surgery; Fetofetal Transfusion - therapy; Gynecology. Andrology. Obstetrics; Humans; Inter-twin septostomy; Medical sciences; Pregnancy; Pregnancy. Fetus. Placenta; Survival Rate; Twin-to-twin transfusion syndrome; Ultrasonography, Prenatal - methods; Inter-twin septostomy; Amniodrainage; Twin-to-twin transfusion syndrome; Fetal outcome; Drainage; Human; Treatment; Pregnancy disorders; Septotomy; Treatment efficiency; Amniotic fluid; Fetofetal transfusion; Fetus; Twin pregnancy; Bibliographic review
• ISSN: 0301-2115; 1872-7654
• DOI: 10.1016/S0301-2115(00)00438-3

Objective: Severe previable twin-to-twin transfusion syndrome (TTTS) is associated with a high fetal loss rate and is therefore usually treated. In this paper, serial amniodrainage and inter-twin septostomy are reviewed in terms of technical aspects and fetal outcome. Study design: A review of the literature using a MEDLINE DATA search between 1990 and 2000 was done in order to describe the mechanisms and technical aspects of both procedures with their physiopathological consequences. In addition, data from our experience with septostomy are given. Results: Amniodrainage increases survival rate, with outcome ranging from 40 to 87% (mean: 56%). Inter-twin septostomy is associated with a mean fetal survival rate ranging from 57 to 83% (mean: 70%). Conclusion: In severe TTTS, amniodrainage and septostomy are simple therapeutic alternatives with a survival rate similar to what is currently reported for laser coagulation of placental vessels.