Triterpene saponins from the fruits of Hedera helix

• Published in: Phytochemistry (Oxford) Vol. 53; no. 8; pp. 905 - 909
• Main Authors: Bedir, E., Kırmızıpekmez, H., Sticher, O., Çalış, İ.
• Format: Journal Article
• Language: English
• Published: OXFORD Elsevier Ltd 01.04.2000; Elsevier
• Subjects: Anti-Inflammatory Agents, Non-Steroidal - chemistry; Anti-Inflammatory Agents, Non-Steroidal - isolation & purification; Anti-Inflammatory Agents, Non-Steroidal - pharmacology; Araliaceae; Bacillus cereus - drug effects; Biochemistry & Molecular Biology; Biological and medical sciences; Candida albicans - drug effects; Chemical constitution; Escherichia coli - drug effects; Fruit - chemistry; Fundamental and applied biological sciences. Psychology; Hedera helix; Helixosides A and B; Life Sciences & Biomedicine; Magnetic Resonance Spectroscopy; Microbial Sensitivity Tests; Oleanolic Acid - analogs & derivatives; Plant physiology and development; Plant Sciences; Plants - chemistry; Saponins - chemistry; Saponins - isolation & purification; Saponins - pharmacology; Science & Technology; Spectrophotometry, Infrared; Staphylococcus epidermidis - drug effects; Triterpenes - chemistry; Triterpenes - isolation & purification; Triterpenes - pharmacology; Triterpenoid saponins; Helixosides A and B; Hedera helix; Araliaceae; Triterpenoid saponins; triterpenoid saponins; PLANTS; helixosides A and B; NATURAL-PRODUCTS; Fruit; Molecular structure; Dicotyledones; Angiospermae; Triterpene; Isolation; Spermatophyta; Medicinal plant; Saponin
• ISSN: 0031-9422; 1873-3700
• DOI: 10.1016/S0031-9422(99)00503-8

Six triterpene saponins, including two new compounds, were isolated from the fruits of Hedera helix L. (Araliaceae). The structures of the new compounds, named helixosides A and B, were established as 3- O-β- D-glucopyranosyl-(1→2)-β- D-glucopyranosyl hederagenin 28- O-β- D-glucopyranosyl-(1→6)-β- D-glucopyranosyl ester, and 3- O-β- D-glucopyranosyl-(1→2)-β- D-glucopyranosyl oleanolic acid 28- O-β- D-glucopyranosyl-(1→6)-β- D-glucopyranosyl ester, respectively, on the basis of chemical and spectral data.