The coexistence of systemic lupus erythematosus and psoriasis

• Published in: Journal of the American Academy of Dermatology Vol. 10; no. 4; pp. 619 - 622
• Main Authors: Hays, Susan B., Camisa, Charles, Luzar, Michael J.
• Format: Journal Article
• Language: English
• Published: New York, NY Mosby, Inc 01.01.1984; Elsevier
• Subjects: Adult; Antibodies - immunology; Antibodies, Antinuclear - immunology; Antigens - immunology; Autoantigens; Biological and medical sciences; Counterimmunoelectrophoresis; Female; Fluorescent Antibody Technique; Humans; Immunodiffusion; Lupus Erythematosus, Systemic - complications; Lupus Erythematosus, Systemic - immunology; Male; Medical sciences; Psoriasis - complications; Psoriasis - immunology; Ribonucleoproteins; RNA, Small Cytoplasmic; Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis; SS-B Antigen; Transcription Factors - immunology; Lupus erythematosus; Concomitant disease; Skin disease; Disseminated; Psoriasis
• ISSN: 0190-9622; 1097-6787
• DOI: 10.1016/S0190-9622(84)80267-4

Systemic and discoid lupus erythernatosus (LE) have both been reported in association with psoriasis. Four additional patients who had systemic LE are reported. All of them had a high titer of antinuclear antibodies (ANAs) and were SS-A(Ro)-negative. Only one patient exhibited photosensitivity. SS-A(Ro) antibodies do not appear to be specific markers for the coexistence of LE and psoriasis, and screening for them in all psoriatics prior to ultraviolet B phototherapy is not recommended. Pitfalls in the management of patients with systemic LE and psoriasis are discussed. (J Am ACAD DERMATOL 10:619–622, 1984.)