Effects of cypermethrin on rainbow trout (Oncorhynchus mykiss)

• Published in: Veterinární medicína Vol. 51; no. 10; pp. 469 - 476
• Main Authors: Velisek, J, Wlasow, T, Gomulka, P, Svobodova, Z, Dobsikova, R, Novotny, L, Dudzik, M
• Format: Journal Article
• Language: English
• Published: Prague Czech Academy of Agricultural Sciences (CAAS) 01.10.2006; Czech Academy of Agricultural Sciences
• Subjects: ACUTE TOXICITY; ALANINA AMINOTRANSFERASA; ALANINE AMINOTRANSFERASE; ALBUMINAS; ALBUMINE; ALBUMINS; ALKALINE PHOSPHATASE; AMMONIA; AMMONIAC; AMONIACO; ANIMAL TISSUES; ASPARTATE AMINOTRANSFERASE; ASPARTATO AMINOTRANSFERASA; AZUCAR EN SANGRE; BAZO; biochemical profile of blood; BLOOD PROTEINS; BLOOD SUGAR; BRANCHIE; BRANQUIAS; CALCIO; CALCIUM; CELL COUNTING; CHOLINESTERASE; CIPERMETRIN; COLINESTERASA; CONTEO DE CELULAS; CREATINA QUINASA; Creatine; CREATINE KINASE; Cyclopropane; CYPERMETHRIN; CYPERMETHRINE; Degeneration; ENSAYO; ERITROCITOS; ERYTHROCYTE; ERYTHROCYTES; Exposure; FORMAS JUVENILES; FOSFATASA ALCALINA; FOSFATOS (SALES); GILLS; GLOBULINAS; GLOBULINE; GLOBULINS; GLUCOSA; GLUCOSE; GRANULOCITOS; GRANULOCYTE; GRANULOCYTES; HAEMATOCRIT; haematological profile; HAEMOGLOBIN; HEMATOCRITE; HEMATOCRITO; Hematology; HEMOGLOBINA; HEMOGLOBINE; Hepatocytes; HISTOPATHOLOGIE; HISTOPATHOLOGY; HISTOPATOLOGIA; http://www.fao.org/aos/agrovoc#c_0; http://www.fao.org/aos/agrovoc#c_11258; http://www.fao.org/aos/agrovoc#c_14992; http://www.fao.org/aos/agrovoc#c_1586; http://www.fao.org/aos/agrovoc#c_15950; http://www.fao.org/aos/agrovoc#c_247; http://www.fao.org/aos/agrovoc#c_25393; http://www.fao.org/aos/agrovoc#c_2659; http://www.fao.org/aos/agrovoc#c_267; http://www.fao.org/aos/agrovoc#c_27963; http://www.fao.org/aos/agrovoc#c_29528; http://www.fao.org/aos/agrovoc#c_3262; http://www.fao.org/aos/agrovoc#c_3279; http://www.fao.org/aos/agrovoc#c_3287; http://www.fao.org/aos/agrovoc#c_33779; http://www.fao.org/aos/agrovoc#c_3462; http://www.fao.org/aos/agrovoc#c_34843; http://www.fao.org/aos/agrovoc#c_349; http://www.fao.org/aos/agrovoc#c_4099; http://www.fao.org/aos/agrovoc#c_4138; http://www.fao.org/aos/agrovoc#c_4139; http://www.fao.org/aos/agrovoc#c_4484; http://www.fao.org/aos/agrovoc#c_4916; http://www.fao.org/aos/agrovoc#c_7097; http://www.fao.org/aos/agrovoc#c_7314; http://www.fao.org/aos/agrovoc#c_7983; http://www.fao.org/aos/agrovoc#c_8700; http://www.fao.org/aos/agrovoc#c_8986; http://www.fao.org/aos/agrovoc#c_9324; http://www.fao.org/aos/agrovoc#c_970; JUVENILE; JUVENILES; KIDNEYS; Kinases; L-Lactate dehydrogenase; LACTATE; LACTATE DEHYDROGENASE; LACTATE DESHYDROGENASE; LACTATES; LACTATO DESHIDROGENASA; LACTATOS; Lactic acid; Lamellae; Leukocytes; Leukocytes (granulocytic); LINFOCITOS; LYMPHOCYTE; LYMPHOCYTES; MONOCITOS; MONOCYTE; MONOCYTES; NUMERATION CELLULAIRE; ONCORHYNCHUS MYKISS; PEAU; Pesticides; PHOSPHATASE ALCALINE; PHOSPHATE (SEL); PHOSPHATES (SALTS); PIEL (ANIMAL); PROTEINAS SANGUINEAS; PROTEINE SANGUINE; pyrethroids; RATE; REIN; RINONES; Salmon; SKIN; SPLEEN; SUBSTANCE TOXIQUE; SUCRE DU SANG; SUSTANCIAS TOXICAS; TEJIDOS ANIMALES; TESTAGE; TESTING; TISSU ANIMAL; Tissues; TOXIC SUBSTANCES; TOXICIDAD AGUDA; TOXICITE AIGUE; Toxicity testing; TRIGLICERIDOS; TRIGLYCERIDE; TRIGLYCERIDES; TROUT; TRUCHA; TRUITE
• ISSN: 0375-8427; 1805-9392
• DOI: 10.17221/5580-VETMED

Acute toxicity tests were carried out in order to assess the effect of cypermethrin on rainbow trout. Results of haematological, biochemical and histopathological tissue examinations of control and experimental groups exposed to Alimetrine 10 EM pesticide preparation (active substance 100 g/L of cypermethrin) were compared. An acute semistatical toxicity test lasting 96 h was performed on rainbow trout juveniles. The 96hLC50 value of Alimethrine 10 EM was 31.4 microg/L. In comparison with control animals, the experimental group showed significantly higher values of plasma ammonia, aspartate aminotransferase, lactate dehydrogenase, creatine kinase, and lactate, and significantly lower values of alkaline phosphatase. A significant decrease in counts of developmental forms of myeloid sequence and segmented neutrophile granulocytes was found in the experimental group. Teleangioectasiae of secondary gill lamellae and degeneration of hepatocytes were observed. No histopathological changes were demonstrated in skin, spleen, cranial and caudal kidney tissues. The cypermethrine-based Alimethrinee 10 EM pesticide preparation was classified as a substance strongly toxic for fish.