Methyl bromide optic atrophy

A 32-year-old fumigation assistant developed systemic and neuro-ophthalmic manifestations of methyl bromide poisoning, including increased serum bromide level (6.6 mg/100 ml), paresthesias and burning dysesthesia on his hands and feet, and visual impairment. Ocular examination showed mild bilateral...

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Bibliographic Details
Published inAmerican journal of ophthalmology Vol. 99; no. 6; p. 715
Main Authors Chavez, C T, Hepler, R S, Straatsma, B R
Format Journal Article
LanguageEnglish
Published United States 15.06.1985
Subjects
Adult
Chronic Disease
Humans
Hydrocarbons, Brominated - poisoning
Male
Neural Conduction
Occupational Diseases
Ophthalmoscopy
Optic Atrophy - chemically induced
Optic Atrophy - pathology
Optic Atrophy - physiopathology
Peripheral Nervous System Diseases - physiopathology
Visual Acuity
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Summary:A 32-year-old fumigation assistant developed systemic and neuro-ophthalmic manifestations of methyl bromide poisoning, including increased serum bromide level (6.6 mg/100 ml), paresthesias and burning dysesthesia on his hands and feet, and visual impairment. Ocular examination showed mild bilateral decrease in vision, temporal optic nerve head pallor, severely attenuated visual-evoked response amplitudes and normal latencies, a normal electroretinogram, an abnormal electrooculogram, and a severe deuteranomalous (green) defect on Farnsworth-Munsell 100-hue testing. His vision had not improved 12 months after the initial exposure.
ISSN:0002-9394
DOI:10.1016/S0002-9394(14)76043-X