Polyphenolic Metabolites from Iris pseudacorus Roots
Five known isoflavonoids ( 6 – 8 , 11 , 16 ), one flavonoid ( 14 ), four hydroxybenzoic acids ( 1 – 4 ), and a new 7-O- β -D-glucopyranoside of 5,7-dihydroxy-2′,6-dimethoxyisoflavone ( 5 ) were isolated from Iris pseudacorus roots and identified. The polyphenol contents in stems and roots of this pl...
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| Published in | Chemistry of natural compounds Vol. 51; no. 3; pp. 451 - 455 |
|---|---|
| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
New York
Springer US
01.05.2015
Springer Nature Springer |
| Subjects | |
| Online Access | Get full text |
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| Summary: | Five known isoflavonoids (
6
–
8
,
11
,
16
), one flavonoid (
14
), four hydroxybenzoic acids (
1
–
4
), and a new 7-O-
β
-D-glucopyranoside of 5,7-dihydroxy-2′,6-dimethoxyisoflavone (
5
) were isolated from Iris pseudacorus roots and identified. The polyphenol contents in stems and roots of this plant were determined. The effect of
6
,
8
,
9
,
11
,
15
, and
16
on the growth of colonies of HT-29 human colon carcinoma cells was studied. It was shown that trans-3-hydroxy-5,7-dimethoxyflavanone (
9
) exhibited pronounced inhibition of tumor-cell colony formation at a dose of 25 μM. |
|---|---|
| ISSN: | 0009-3130 1573-8388 |
| DOI: | 10.1007/s10600-015-1313-9 |