A miniaturized carbon dioxide gas sensor based on sensing of pH-sensitive hydrogel swelling with a pressure sensor
A measurement concept has been realized for the detection of carbon dioxide, where the CO(2) induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantification of the partial pressure of CO(2) (Pco(2)) in the...
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Published in | Biomedical microdevices Vol. 7; no. 3; pp. 197 - 204 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
United States
Springer Nature B.V
01.09.2005
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Abstract | A measurement concept has been realized for the detection of carbon dioxide, where the CO(2) induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantification of the partial pressure of CO(2) (Pco(2)) in the stomach as diagnosis for gastrointestinal ischemia. The principle is put to the proof by examining the sensor response to changes in Pco(2). Furthermore, the response time, temperature-sensitivity and resolution are determined. The sensor responds well to changes in Pco(2) with a maximum pressure generation of 0.29 x 10(5) Pa at 20 kPa CO(2). The 90% response time varies between 1.5 and 4.5 minutes at 37( composite function)C. The sensor shows a linear temperature-sensitivity which can easily be compensated for, and enables detection of Pco(2) changes as small as 0.5 kPa CO(2). |
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AbstractList | A measurement concept has been realized for the detection of carbon dioxide, where the CO(2) induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantification of the partial pressure of CO(2) (Pco(2)) in the stomach as diagnosis for gastrointestinal ischemia. The principle is put to the proof by examining the sensor response to changes in Pco(2). Furthermore, the response time, temperature-sensitivity and resolution are determined. The sensor responds well to changes in Pco(2) with a maximum pressure generation of 0.29 x 10(5) Pa at 20 kPa CO(2). The 90% response time varies between 1.5 and 4.5 minutes at 37( composite function)C. The sensor shows a linear temperature-sensitivity which can easily be compensated for, and enables detection of Pco(2) changes as small as 0.5 kPa CO(2). A measurement concept has been realized for the detection of carbon dioxide, where the CO sub(2) induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantification of the partial pressure of CO sub(2) (Pco sub(2)) in the stomach as diagnosis for gastrointestinal ischemia. The principle is put to the proof by examining the sensor response to changes in Pco sub(2). Furthermore, the response time, temperature-sensitivity and resolution are determined. The sensor responds well to changes in Pco sub(2) with a maximum pressure generation of 0.29 x 10 super(5) Pa at 20 kPa CO sub(2). The 90% response time varies between 1.5 and 4.5 minutes at 37 super([compfn])C. The sensor shows a linear temperature-sensitivity which can easily be compensated for, and enables detection of Pco sub(2) changes as small as 0.5 kPa CO sub(2). A measurement concept has been realized for the detection of carbon dioxide, where the CO2 induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantification of the partial pressure of CO2 (Pco2) in the stomach as diagnosis for gastrointestinal ischemia. The principle is put to the proof by examining the sensor response to changes in Pco2. Furthermore, the response time, temperature-sensitivity and resolution are determined. The sensor responds well to changes in Pco2 with a maximum pressure generation of 0.29× 105 Pa at 20 kPa CO2. The 90% response time varies between 1.5 and 4.5 minutes at 37[composite function]C. The sensor shows a linear temperature-sensitivity which can easily be compensated for, and enables detection of Pco2 changes as small as 0.5 kPa CO2. A measurement concept has been realized for the detection of carbon dioxide, where the CO(2) induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantification of the partial pressure of CO(2) (Pco(2)) in the stomach as diagnosis for gastrointestinal ischemia. The principle is put to the proof by examining the sensor response to changes in Pco(2). Furthermore, the response time, temperature-sensitivity and resolution are determined. The sensor responds well to changes in Pco(2) with a maximum pressure generation of 0.29 x 10(5) Pa at 20 kPa CO(2). The 90% response time varies between 1.5 and 4.5 minutes at 37([compfn])C. The sensor shows a linear temperature-sensitivity which can easily be compensated for, and enables detection of Pco(2) changes as small as 0.5 kPa CO(2). |
Author | van den Berg, A Olthuis, W Bomer, J Bergveld, P Herber, S |
Author_xml | – sequence: 1 givenname: S surname: Herber fullname: Herber, S email: s.herber@utwente.nl organization: Faculty of Electrical Engineering, Mathematics & Computer Science, Laboratory of Biosensors, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands. s.herber@utwente.nl – sequence: 2 givenname: J surname: Bomer fullname: Bomer, J – sequence: 3 givenname: W surname: Olthuis fullname: Olthuis, W – sequence: 4 givenname: P surname: Bergveld fullname: Bergveld, P – sequence: 5 givenname: A surname: van den Berg fullname: van den Berg, A |
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Snippet | A measurement concept has been realized for the detection of carbon dioxide, where the CO(2) induced pressure generation by an enclosed pH-sensitive hydrogel... A measurement concept has been realized for the detection of carbon dioxide, where the CO2 induced pressure generation by an enclosed pH-sensitive hydrogel is... A measurement concept has been realized for the detection of carbon dioxide, where the CO sub(2) induced pressure generation by an enclosed pH-sensitive... |
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SubjectTerms | Biological Assay - instrumentation Biological Assay - methods Carbon Dioxide - analysis Carbon Dioxide - chemistry Equipment Design Equipment Failure Analysis Hydrogels - chemistry Hydrogen-Ion Concentration Ion-Selective Electrodes Microelectrodes Miniaturization - methods Osmotic Pressure Transducers, Pressure |
Title | A miniaturized carbon dioxide gas sensor based on sensing of pH-sensitive hydrogel swelling with a pressure sensor |
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