A miniaturized carbon dioxide gas sensor based on sensing of pH-sensitive hydrogel swelling with a pressure sensor

A measurement concept has been realized for the detection of carbon dioxide, where the CO(2) induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantification of the partial pressure of CO(2) (Pco(2)) in the...

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Published inBiomedical microdevices Vol. 7; no. 3; pp. 197 - 204
Main Authors Herber, S, Bomer, J, Olthuis, W, Bergveld, P, van den Berg, A
Format Journal Article
LanguageEnglish
Published United States Springer Nature B.V 01.09.2005
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Abstract A measurement concept has been realized for the detection of carbon dioxide, where the CO(2) induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantification of the partial pressure of CO(2) (Pco(2)) in the stomach as diagnosis for gastrointestinal ischemia. The principle is put to the proof by examining the sensor response to changes in Pco(2). Furthermore, the response time, temperature-sensitivity and resolution are determined. The sensor responds well to changes in Pco(2) with a maximum pressure generation of 0.29 x 10(5) Pa at 20 kPa CO(2). The 90% response time varies between 1.5 and 4.5 minutes at 37( composite function)C. The sensor shows a linear temperature-sensitivity which can easily be compensated for, and enables detection of Pco(2) changes as small as 0.5 kPa CO(2).
AbstractList A measurement concept has been realized for the detection of carbon dioxide, where the CO(2) induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantification of the partial pressure of CO(2) (Pco(2)) in the stomach as diagnosis for gastrointestinal ischemia. The principle is put to the proof by examining the sensor response to changes in Pco(2). Furthermore, the response time, temperature-sensitivity and resolution are determined. The sensor responds well to changes in Pco(2) with a maximum pressure generation of 0.29 x 10(5) Pa at 20 kPa CO(2). The 90% response time varies between 1.5 and 4.5 minutes at 37( composite function)C. The sensor shows a linear temperature-sensitivity which can easily be compensated for, and enables detection of Pco(2) changes as small as 0.5 kPa CO(2).
A measurement concept has been realized for the detection of carbon dioxide, where the CO sub(2) induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantification of the partial pressure of CO sub(2) (Pco sub(2)) in the stomach as diagnosis for gastrointestinal ischemia. The principle is put to the proof by examining the sensor response to changes in Pco sub(2). Furthermore, the response time, temperature-sensitivity and resolution are determined. The sensor responds well to changes in Pco sub(2) with a maximum pressure generation of 0.29 x 10 super(5) Pa at 20 kPa CO sub(2). The 90% response time varies between 1.5 and 4.5 minutes at 37 super([compfn])C. The sensor shows a linear temperature-sensitivity which can easily be compensated for, and enables detection of Pco sub(2) changes as small as 0.5 kPa CO sub(2).
A measurement concept has been realized for the detection of carbon dioxide, where the CO2 induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantification of the partial pressure of CO2 (Pco2) in the stomach as diagnosis for gastrointestinal ischemia. The principle is put to the proof by examining the sensor response to changes in Pco2. Furthermore, the response time, temperature-sensitivity and resolution are determined. The sensor responds well to changes in Pco2 with a maximum pressure generation of 0.29× 105 Pa at 20 kPa CO2. The 90% response time varies between 1.5 and 4.5 minutes at 37[composite function]C. The sensor shows a linear temperature-sensitivity which can easily be compensated for, and enables detection of Pco2 changes as small as 0.5 kPa CO2.
A measurement concept has been realized for the detection of carbon dioxide, where the CO(2) induced pressure generation by an enclosed pH-sensitive hydrogel is measured with a micro pressure sensor. The application of the sensor is the quantification of the partial pressure of CO(2) (Pco(2)) in the stomach as diagnosis for gastrointestinal ischemia. The principle is put to the proof by examining the sensor response to changes in Pco(2). Furthermore, the response time, temperature-sensitivity and resolution are determined. The sensor responds well to changes in Pco(2) with a maximum pressure generation of 0.29 x 10(5) Pa at 20 kPa CO(2). The 90% response time varies between 1.5 and 4.5 minutes at 37([compfn])C. The sensor shows a linear temperature-sensitivity which can easily be compensated for, and enables detection of Pco(2) changes as small as 0.5 kPa CO(2).
Author van den Berg, A
Olthuis, W
Bomer, J
Bergveld, P
Herber, S
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/16133807$$D View this record in MEDLINE/PubMed
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Snippet A measurement concept has been realized for the detection of carbon dioxide, where the CO(2) induced pressure generation by an enclosed pH-sensitive hydrogel...
A measurement concept has been realized for the detection of carbon dioxide, where the CO2 induced pressure generation by an enclosed pH-sensitive hydrogel is...
A measurement concept has been realized for the detection of carbon dioxide, where the CO sub(2) induced pressure generation by an enclosed pH-sensitive...
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StartPage 197
SubjectTerms Biological Assay - instrumentation
Biological Assay - methods
Carbon Dioxide - analysis
Carbon Dioxide - chemistry
Equipment Design
Equipment Failure Analysis
Hydrogels - chemistry
Hydrogen-Ion Concentration
Ion-Selective Electrodes
Microelectrodes
Miniaturization - methods
Osmotic Pressure
Transducers, Pressure
Title A miniaturized carbon dioxide gas sensor based on sensing of pH-sensitive hydrogel swelling with a pressure sensor
URI https://www.ncbi.nlm.nih.gov/pubmed/16133807
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