The Edinburgh Postnatal Depression Scale (EPDS) and the detection of major depressive disorders in early postpartum: some concerns about false negatives

• Published in: Journal of affective disorders Vol. 61; no. 1; pp. 107 - 112
• Main Authors: Guedeney, N., Fermanian, J., Guelfi, J.D., Kumar, R.C.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.12.2000; Elsevier
• Subjects: Adult; Biological and medical sciences; Depression, Postpartum - diagnosis; Depressive Disorder, Major - diagnosis; EPDS; False negative; False Negative Reactions; Female; Humans; Medical sciences; Postnatal depression; Psychology. Psychoanalysis. Psychiatry; Psychometrics. Diagnostic aid systems; Psychomotor Disorders - diagnosis; Psychomotor Disorders - epidemiology; Psychomotor retardation; Psychopathology. Psychiatry; Severity of Illness Index; Surveys and Questionnaires; Techniques and methods; Time Factors; EPDS; Postnatal depression; False negative; Psychomotor retardation; Mood disorder; Human; Evaluation scale; Depression; Psychometrics; Medical screening; Case study; Test validation; Construct validity; Symptomatology; Postnatal; Edinburgh Postnatal Depression Scale; Critical study; Female; Test scoring
• ISSN: 0165-0327; 1573-2517
• DOI: 10.1016/S0165-0327(99)00186-X

This paper presents a phenomenological study of three false negative cases according to the Edinburgh Postnatal Depression Scale (EPDS) of major depressive disorder identified by a semi-structured clinical interview. In a study of 87 unselected women with 23 of them suffering from a major depressive disorder (according to the Research Diagnostic Criteria), three cases of major depressive disorders were not identified as potential cases by the EPDS. The symptomatology of these three false negative cases was also assessed by a semi-structured interview (Present State Examination). Comparisons between EPDS scores and the scores of two other self report questionnaires (the General Health Questionnaire-28 and the Center for Epidemiologic Studies-Depression Scale) suggest that EPDS is better at identifying depressed postnatal women with anhedonic and anxious symptomatology rather than those whose depression presents mainly with psychomotor retardation.