Relationship between SCL-90, Maudsley Personality Inventory and CCK4-induced intracellular calcium response in T cells

• Published in: Psychiatry research Vol. 81; no. 3; pp. 381 - 386
• Main Authors: Akiyoshi, Jotaro, Yamauchi, Chiyo, Furuta, Mariko, Katsuragi, Satomi, Kohno, Yoshiko, Yamamoto, Yukiko, Miyamoto, Masafumi, Tsutsumi, Takashi, Isogawa, Koichi, Fujii, Isao
• Format: Journal Article
• Language: English
• Published: Shannon Elsevier Ireland Ltd 14.12.1998; Elsevier
• Subjects: Adult; Anatomical correlates of behavior; Anxiety Disorders - diagnosis; Anxiety Disorders - physiopathology; Behavioral psychophysiology; Biological and medical sciences; Calcium; Calcium - metabolism; Calcium Channels - drug effects; Calcium Channels - physiology; Cholecystokinin; Extraversion (Psychology); Female; Fundamental and applied biological sciences. Psychology; Humans; Intracellular calcium mobilization; Introversion (Psychology); Male; Maudsley Personality Inventory; Personality Disorders - diagnosis; Personality Disorders - physiopathology; Personality Inventory - statistics & numerical data; Psychology. Psychoanalysis. Psychiatry; Psychology. Psychophysiology; Receptor, Cholecystokinin B; Receptors, Cholecystokinin - drug effects; Receptors, Cholecystokinin - physiology; SCL-90; T cells; T-Lymphocytes - drug effects; Tetragastrin; Maudsley Personality Inventory; Cholecystokinin; Calcium; T cells; Intracellular calcium mobilization; SCL-90; Human; Neuroticism; Social behavior; Extraversion introversion; Tetrapeptide; T-Lymphocyte; Personality; Intracellular
• ISSN: 0165-1781; 1872-7123
• DOI: 10.1016/S0165-1781(98)00116-4

This study examined the relationship between the Symptom Checklist 90 (SCL-90), Maudsley Personality Inventory (MPI) and cholecystokinin 4 (CCK4)-induced intracellular calcium response in T cells. Fifty-two normal volunteers were 37 males and 15 females; they ranged in age from 23 to 44 years. Measures included CCK4-induced intracellular calcium response in T cells, SCL-90 scores, and MPI. Paranoid ideation and interpersonal sensitivity in SCL-90 showed a significant negative association with CCK4-induced intracellular calcium response. Absent were sex differences and extroversion and neuroticism correlations. There were no significant differences between men and women in SCL-90 or MPI scores. There was no correlation among extroversion and neuroticism and CCK4-induced intracellular calcium response. CCKB receptor function might play a role in paranoid ideation and interpersonal sensitivity.