Osteoporosis in patients with cystic fibrosis

Decreased bone density and increased risk of fractures are seen in patients with cystic fibrosis. Suboptimal vitamin D levels, nutrition problems, hypogonadism, inactivity, corticosteroid use, and cytokines may contribute to the low bone mass seen in these patients. Treatment recommendations must be...

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Bibliographic Details
Published inClinics in chest medicine Vol. 19; no. 3; p. 555
Main Authors Ott, S M, Aitken, M L
Format Journal Article
LanguageEnglish
Published United States 01.09.1998
Subjects
Absorptiometry, Photon
Cystic Fibrosis - complications
Cystic Fibrosis - physiopathology
Cystic Fibrosis - surgery
Fractures, Bone - complications
Glucocorticoids - metabolism
Humans
Lung Transplantation - physiology
Osteoporosis - complications
Osteoporosis - diagnosis
Osteoporosis - physiopathology
Vitamin D - metabolism
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Summary:Decreased bone density and increased risk of fractures are seen in patients with cystic fibrosis. Suboptimal vitamin D levels, nutrition problems, hypogonadism, inactivity, corticosteroid use, and cytokines may contribute to the low bone mass seen in these patients. Treatment recommendations must be individualized and may include nutrition, vitamin D, estrogen or testosterone, and exercise. In high-risk patients calcitonin or growth hormone could be considered.
ISSN:0272-5231
DOI:10.1016/S0272-5231(05)70100-3