Proton magnetic resonance spectroscopy ( 1H-MRS) of the thalamus in schizophrenia

This study applied 1H-MRS in the thalamus of schizophrenic patients and healthy subjects. There were no differences in the metabolite ratios (NAA/Cr, Cho/Cr or mI/Cr) between the two groups. Relationships were noted between NAA/Cr and age in patients with a trend toward this correlation in controls,...

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Published inEuropean psychiatry Vol. 15; no. 8; pp. 489 - 491
Main Authors Delamillieure, P, Constans, J.M, Fernandez, J, Brazo, P, Dollfus, S
Format Journal Article
LanguageEnglish
Published Paris Elsevier SAS 01.12.2000
Elsevier
Subjects
Adult
Adult and adolescent clinical studies
aging
Biological and medical sciences
Female
Functional Laterality - physiology
Humans
Magnetic Resonance Spectroscopy - methods
Male
Medical sciences
N-acetyl-aspartate
Protons
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
Schizophrenia
Schizophrenia - metabolism
spectroscopy
thalamus
Thalamus - metabolism
N-acetyl-aspartate
aging
schizophrenia
spectroscopy
thalamus
Human
Acyltransferases
Senescence
Hemispheric specialization
Aspartate N-acetyltransferase
Healthy subject
Enzyme
Transferases
Central nervous system
Schizophrenia
NMR spectrometry
Metabolism
Psychosis
Thalamus
Clinical investigation
Laterality
Age
Comparative study
Brain (vertebrata)
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Summary:This study applied 1H-MRS in the thalamus of schizophrenic patients and healthy subjects. There were no differences in the metabolite ratios (NAA/Cr, Cho/Cr or mI/Cr) between the two groups. Relationships were noted between NAA/Cr and age in patients with a trend toward this correlation in controls, suggesting an effect of age on the metabolism of the thalamus.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0924-9338
1778-3585
DOI:10.1016/S0924-9338(00)00522-8