Delayed hypersensitivity reaction after infusion of nonionic intravenous contrast material for an excretory urogram: a case report and review of the literature

Delayed adverse reactions to ionic and nonionic intravenous contrast media have been reported previously. We report a case in which delayed hypersensitivity to iohexol, a nonionic intravenous contrast agent commonly used in excretory urography, resulted in a bi-phasic allergic response. This reactio...

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Bibliographic Details
Published inThe Journal of urology Vol. 153; no. 5; p. 1641
Main Authors Stovsky, M D, Seftel, A D, Resnick, M I
Format Journal Article
LanguageEnglish
Published United States 01.05.1995
Subjects
Aged
Contrast Media - adverse effects
Drug Eruptions - etiology
Drug Hypersensitivity - etiology
Humans
Hypersensitivity, Delayed - chemically induced
Iohexol - adverse effects
Male
Time Factors
Urography
Urticaria - chemically induced
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Summary:Delayed adverse reactions to ionic and nonionic intravenous contrast media have been reported previously. We report a case in which delayed hypersensitivity to iohexol, a nonionic intravenous contrast agent commonly used in excretory urography, resulted in a bi-phasic allergic response. This reaction consisted of a mild post-infusion episode of urticaria, which preceded and was clinically distinct from a moderately severe dermatological eruption. The episode of urticaria was self-limited. The dermatological reaction was treated successfully with antihistamine therapy.
ISSN:0022-5347
DOI:10.1016/S0022-5347(01)67487-1