The effects of lactated Ringer's solution infusion on cardiac output changes after spinal anesthesia

• Published in: Anesthesia and analgesia Vol. 92; no. 3; pp. 710 - 714
• Main Authors: KAMENIK, Mirt, PAVER-ERZEN, Vesna
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott 01.03.2001
• Subjects: Adult; Anesthesia; Anesthesia, Spinal; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Blood Pressure - drug effects; Cardiac Output - drug effects; Female; Humans; Isotonic Solutions - pharmacology; Local anesthesia. Pain (treatment); Male; Medical sciences; Middle Aged; Ringer's Lactate; Vascular Resistance - drug effects; Heart; Human; Regional anesthesia; Ringer lactate; Intravenous administration; Electrolyte solution; Crystalloid solution; Perfusion; Hemodynamics; Intrathecal administration; Blood flow
• ISSN: 0003-2999; 1526-7598
• DOI: 10.1097/00000539-200103000-00030

We evaluated the effects of an infusion of lactated Ringer's (LR) solution on changes in cardiac output (CO) after spinal anesthesia. Seventy-five patients scheduled for lower extremity surgery under spinal anesthesia were studied. We measured CO (impedance cardiography method) and blood pressure for 25 min before and 30 min after spinal anesthesia. Patients were randomly assigned to three groups. In the No Infusion group, no LR solution was given during the period of measurements. The LR Before group received 12 mL/kg of LR solution within 20 min before spinal anesthesia. The LR After group received 12 mL/kg of LR solution within 20 min starting immediately after spinal anesthesia. After spinal anesthesia, CO decreased by 13.9% in the No Infusion group. In the LR Before group, CO increased after the infusion by 20% and returned to baseline value 30 min after spinal anesthesia. In the LR After group, CO increased after spinal anesthesia, and 30 min after spinal anesthesia, CO was 11.3% above baseline. We conclude that the decrease in CO after spinal anesthesia can be prevented by the infusion of an LR solution, with CO reaching the highest value while the infusion is running. We studied the effects of lactated Ringer's solution infusion on cardiac output changes after spinal anesthesia. If the patients received no infusion, cardiac output decreased after spinal anesthesia. However, if the patients received lactated Ringer's solution infusion, cardiac output was maintained.