Easier patch testing with TRUE Test

• Published in: Journal of the American Academy of Dermatology Vol. 20; no. 3; pp. 447 - 453
• Main Authors: Fischer, Torkel, Maibach, Howard I.
• Format: Journal Article
• Language: English
• Published: New York, NY Mosby, Inc 01.03.1989; Elsevier
• Subjects: Allergic diseases; Biological and medical sciences; Dermatitis, Contact - diagnosis; Evaluation Studies as Topic; False Negative Reactions; False Positive Reactions; Humans; Immunopathology; Medical sciences; Patch Tests - adverse effects; Patch Tests - instrumentation; Safety; Skin allergic diseases. Stinging insect allergies; Skin Tests - instrumentation; Allergy; Immunopathology; Skin disease; Contact dermatitis; Skin test
• ISSN: 0190-9622; 1097-6787
• DOI: 10.1016/S0190-9622(89)70056-6

TRUE Test, a standardized, ready-to-apply patch test system, is made from polyester covered with a film of allergens incorporated in a hydrophilic polymer. The patches are mounted on nonwoven cellulose tape with acrylic adhesive, covered with siliconized plastic, and packed in an air-tight and light-impermeable envelope. When the test strip is taped on the skin, perspiration hydrates the film and transforms it to a gel, which causes the allergen to be released, The first panel of 12 allergens and allergen mixes is standardized and tested for stability in vitro and in vivo. The accuracy of the test panel has been certified in international multicenter studies by comparing it with present patch test techniques. A second panel of 11 more allergens was completed in 1988. The two test panels include the full standard panel of the North American Contact Dermatitis Group.