The prolongation of survival in mice by dietary antioxidants depends on their age by the start of feeding this diet

The effect of daily dietary supplements of an antioxidant mixture (AM) consisting of beta carotene, alpha tocopherol, ascorbic acid, rutin, selenium, and zinc on the survival of male C57BL/6 mice starting at 2, 9, 16, and 23 months of age was investigated. The survival of mice given AM starting at 2...

Full description

Saved in:
Bibliographic Details
Published inMechanisms of ageing and development Vol. 92; no. 2; pp. 227 - 234
Main Authors Bezlepkin, Vladimir G, Sirota, Nikolai P, Gaziev, Azhub I
Format Journal Article
LanguageEnglish
Published Shannon Elsevier Ireland Ltd 20.12.1996
Elsevier Science
Subjects
Aging
Aging - physiology
Animals
Antioxidants - pharmacology
Diet
Dietary antioxidants
Longevity - physiology
Male
Mice
Mice, Inbred C57BL
Survival of mice
Aging
Dietary antioxidants
Survival of mice
Online AccessGet full text

Cover

More Information
Summary:The effect of daily dietary supplements of an antioxidant mixture (AM) consisting of beta carotene, alpha tocopherol, ascorbic acid, rutin, selenium, and zinc on the survival of male C57BL/6 mice starting at 2, 9, 16, and 23 months of age was investigated. The survival of mice given AM starting at 2 and 9 months of age was found to increase significantly (from 86 to 108 days) compared to the control. The times, of 50, 90, and 100% mortality in mice given AM starting at 2 and 9 months of age increased by 16–9.5% compared to the control, whereas in mice given AM, starting at 16 and 23 months of age, no effect was observed.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0047-6374
1872-6216
DOI:10.1016/S0047-6374(96)01840-4