Myelodysplastic syndrome associated with Griscelli syndrome

• Published in: Leukemia research Vol. 22; no. 9; pp. 859 - 862
• Main Authors: Cetin, M, Hiçsönmez, G, Göğüş, S
• Format: Journal Article
• Language: English
• Published: Oxford Elsevier Ltd 01.09.1998; Elsevier Science
• Subjects: Biological and medical sciences; Children; Griscelli syndrome; Hematologic and hematopoietic diseases; Hepatomegaly; Humans; Immunity, Cellular; Immunologic Deficiency Syndromes - complications; Infant; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis; Male; MDS; Medical sciences; Myelodysplastic Syndromes - complications; Pigmentation Disorders - complications; Splenomegaly; Syndrome; MDS; Griscelli syndrome; Children; Human; Immunopathology; Skin disease; Pigmentation disorder; Albinism; Metabolic diseases; Male; Infant; Malignant hemopathy; Uvea disease; Enzymopathy; Immune deficiency; Myelodysplastic syndrome; Refractory anemia with excess blasts; Genetic disease; Case study; Eye disease; Association; Aminoacid disorder
• ISSN: 0145-2126; 1873-5835
• DOI: 10.1016/S0145-2126(98)00075-7

Myelodysplastic syndrome (MDS) in children has been reported to be associated with various constitutional anomalies; however, it has not been described previously in patients with Griscelli syndrome (GS). In this report, we present a case with GS and refractory anemia with an excess of blasts. We believe that careful evaluation of peripheral blood and bone marrow could increase the number of patients who are found to have GS-associated MDS.