Henoch-Schönlein purpura presenting with multiplex gastrointestinal manifestations and massive nephrotic syndrome in adulthood -- a case report

Henoch-Schönlein purpura (HSP) is a systemic small vessel vasculitis mainly affecting children. We report a case of a 49-year-old woman with severe gastrointestinal and renal involvement of HSP. Endoscopy revealed more characteristic findings in the terminal ileum than in the gastric antrum. Histolo...

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Published inCentral European journal of medicine Vol. 3; no. 4; pp. 521 - 524
Main Authors Klaudia, Farkas, Tamás, Molnár, Ferenc, Nagy, László, Tiszlavicz, István, Németh, Éva, Kemény, Erika, Varga, Tibor, Wittmann
Format Journal Article
LanguageEnglish
Published Heidelberg Heidelberg : SP Versita 01.12.2008
SP Versita
Versita
Walter de Gruyter GmbH
Subjects
Adulthood
Biomedicine
Case Report
Henoch-Schönlein purpura
Internal Medicine
Maternal and Child Health
Medicine
Medicine & Public Health
Nephrotic syndrome
Reproductive Medicine
Surgery
Henoch-Schönlein purpura
Nephrotic syndrome
Adulthood
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Summary:Henoch-Schönlein purpura (HSP) is a systemic small vessel vasculitis mainly affecting children. We report a case of a 49-year-old woman with severe gastrointestinal and renal involvement of HSP. Endoscopy revealed more characteristic findings in the terminal ileum than in the gastric antrum. Histological examinations of the biopsy samples from the ileum, antrum, skin and kidney confirmed the diagnosis of HSP. Parenteral corticosteroid therapy led to a rapid improvement of the gastrointestinal symptoms, but because of the excessive proteinuria intravenous cyclophosphamide therapy had to be introduced.
Bibliography:http://dx.doi.org/10.2478/s11536-008-0060-8
ISSN:1644-3640
1895-1058
2391-5463
1644-3640
2391-5463
DOI:10.2478/s11536-008-0060-8