Impact of admission blood glucose levels on prognosis of elderly patients with ST elevation myocardial infarction treated by primary percutaneous coronary intervention

• Published in: Journal of geriatric cardiology : JGC Vol. 10; no. 4; pp. 310 - 316
• Main Authors: Ekmekci, Ahmet, Uluganyan, Mahmut, Tufan, Fatif, Uyarel, Huseyin, Karaca, Gurkan, Kul, Seref, Gungor, Barış, Ertas, Gokhan, Erer, Betul, Sayar, Nurten, Gul, Mehmet, Eren, Mehmet
• Format: Journal Article
• Language: English
• Published: China Department of Cardiology, Dr.Siyami Ersek Thoracic and Cardiovascular Surgery Center Training and Research Hospital, Tibbiye Caddesi, 34000 Istanbul, Turkey%Department of Cardiology, Kadirli State Hospital, Toki Caddesi, 8075 Osmaniye, Turkey%Department of Geriatric, Istanbul University Medical Hospital, Vatan Cadddessi, 34000 Istanbul, Turkey%Department of Cardiology, Bezmialem Vakif University Medical Hospital, Vatan Caddesi, 34000 Istanbul, Turkey 01.12.2013; Science Press
• Subjects: Major adverse cardiac events; In-hospital mortality; Admission hyperglycemia; Long-term mortality; Elderly patients
• ISSN: 1671-5411
• DOI: 10.3969/j.issn.1671-5411.2013.04.002

Admission hyperglycemia in acute myocardial infarction (MI) is related with increased in-hospital and long term mortality and major cardiac adverse events. We aimed to investigate how admission hyperglycemia affects the short and long term outcomes in elderly patients (> 65 years) after primary percutaneous coronary intervention for ST elevation myocardial infarction. We retrospectively analyzed 677 consecutive elderly patients (mean age 72.2 ± 5.4). Patients were divided into two groups according to admission blood glucose levels. Group 1: low glucose group (LLG), glucose < 168 mg/dL; and Group 2: high glucose group (HGG), glucose > 168 mg/dL. In-hospital, long term mortality and in-hospital major adverse cardiac events were higher in the high admission blood glucose group (P < 0.001). Multivariate regression analysis showed: Killip > 1, post-thrombolysis in MI < 3 and admission blood glucose levels were independent predictors of in-hospital adverse cardiac events (P < 0.001). Admission hyperglycemia in elderly patients presented with ST elevation myocardial infarction is an independent predictor of in-hospital major adverse cardiac events and is associated with in-hospital and long term mortality.