Cytomegalovirus cholangitis presenting with recurrent hemobilia

• Published in: European journal of clinical microbiology & infectious diseases Vol. 24; no. 9; pp. 634 - 636
• Main Authors: TLEYJEH, I. M, GEORGESCU, G, VIRK, A, BARAJAS, E. D, MIRZOYEV, Z, ANAVEKAR, N, BADDOUR, L. M
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.09.2005; Springer Nature B.V
• Subjects: Adrenal Cortex Hormones - adverse effects; Antiviral Agents - therapeutic use; Bacterial diseases; Bacterial diseases of the digestive system and abdomen; Biological and medical sciences; Cholangitis; Cholangitis - drug therapy; Cholangitis - etiology; Cholangitis - surgery; Cholecystostomy; Corticoids; Cytomegalovirus; Cytomegalovirus Infections - drug therapy; Cytomegalovirus Infections - etiology; Ganciclovir; Ganciclovir - therapeutic use; Gastroenterology. Liver. Pancreas. Abdomen; Hemobilia - etiology; Hemobilia - surgery; Human bacterial diseases; Human immunodeficiency virus; Humans; Hypereosinophilic Syndrome - complications; Hypereosinophilic Syndrome - drug therapy; Infections; Infectious diseases; Liver. Biliary tract. Portal circulation. Exocrine pancreas; Male; Medical sciences; Middle Aged; Other diseases. Semiology; Recurrence; Relapse; Hemobilia; Herpesviridae; Cholangitis; Biliary tract disease; Betaherpesvirinae; Hemorrhage; Human cytomegalovirus; Infection; Virus; Symptomatology; Viral disease; Bacteriosis; Digestive diseases; Inaugural sign
• ISSN: 0934-9723; 1435-4373
• DOI: 10.1007/s10096-005-0016-8

Cytomegalovirus (CMV) cholangitis is a rare manifestation of CMV infection that has previously been described only in HIV-infected patients and solid-organ-transplant recipients. Reported here is a case of CMV cholangitis that occurred in a patient on chronic corticosteroid therapy who presented with recurrent hemobilia and biliary obstruction and was successfully treated with ganciclovir and cholecystostomy. A search of the medical literature revealed no previous case of this kind.