Radiological and pathological features of AIDS-related polypoid cholangitis

• Published in: Clinical radiology Vol. 48; no. 5; pp. 307 - 310
• Main Authors: Collins, C.D., Forbes, A., Harcourt-Webster, J.N., Francis, N.D., Gleeson, J.A., Gazzard, B.G.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier Ltd 01.11.1993; Elsevier
• Subjects: Acquired Immunodeficiency Syndrome - complications; Adult; AIDS/HIV; Bile Duct Neoplasms - diagnostic imaging; Bile Ducts, Intrahepatic - pathology; Biological and medical sciences; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis, Sclerosing - complications; Cholangitis, Sclerosing - diagnostic imaging; Cholangitis, Sclerosing - pathology; Common Bile Duct - pathology; Female; Humans; Immunodeficiencies; Immunodeficiencies. Immunoglobulinopathies; Immunopathology; Male; Medical sciences; Polyps - diagnostic imaging; Infection; Human; Immunopathology; Pathology; Radiodiagnosis; Viral disease; Digestive diseases; Complication; Exploration; AIDS; Hemopathy; Sclerosing cholangitis
• ISSN: 0009-9260; 1365-229X
• DOI: 10.1016/S0009-9260(05)81236-X

A review of the radiographs obtained at ERCP from 31 patients with AIDS-related sclerosing cholangitis (ARSC) demonstrated intraluminal polypoidal defects within the common bile duct and larger intrahepatic ducts in eight cases (26%). The radiological features from this subgroup are described and correlated with the microbiological and histological findings from biopsy specimens including two patients who underwent post-mortem examination. At microscopy the polypoid lesions were demonstrated to consist of granulation tissue. The presence of these polyps did not adversely affect the prognosis nor were they associated with any particular infective agent. We propose recognizing the existence of this entity by the term AIDS-related polypoid cholangitis (ARPC).