Effects of granuloma formation at site of vasovasostomy

Spermatic granulomas forming after vasectomy reversal have been thought to mechanically compromise the anastomosis. We have studied the physiologic effects of vasectomy and vasovasostomy in rats. Following delayed microsurgical vasovasostomy, fluid flow through the anastomosis and cauda epididymidal...

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Bibliographic Details
Published inThe Journal of urology Vol. 139; no. 4; p. 853
Main Authors Carey, P O, Howards, S S, Flickinger, C J, Herr, J C, Gallien, T N, Caloras, D, Spell, D R
Format Journal Article
LanguageEnglish
Published United States 01.04.1988
Subjects
Animals
Genital Diseases, Male - physiopathology
Granuloma - physiopathology
Male
Postoperative Complications - physiopathology
Rats
Rats, Inbred Strains
Spermatozoa
Vas Deferens - physiopathology
Vasovasostomy
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Summary:Spermatic granulomas forming after vasectomy reversal have been thought to mechanically compromise the anastomosis. We have studied the physiologic effects of vasectomy and vasovasostomy in rats. Following delayed microsurgical vasovasostomy, fluid flow through the anastomosis and cauda epididymidal hydrostatic pressure are not significantly different in tracts that form, or do not form, sperm granulomas at the anastomosis. Given a properly performed microsurgical vasectomy reversal, a sperm granuloma arising from a small leak does not appear to mechanically compromise the anastomosis in the rat. Fertility after vasovasostomy is not significantly reduced in rats with granulomas.
ISSN:0022-5347
DOI:10.1016/S0022-5347(17)42661-9