Biological roles of piRNAs in colorectal cancer

Colorectal cancer (CRC) is one of the most common malignancies worldwide and a major cause of cancer-related deaths. Numerous studies have suggested that piwi-interacting RNAs (piRNAs), a new type of non-coding RNA (ncRNA), are closely related to the occurrence and development of cancer. piRNAs have...

Full description

Saved in:
Bibliographic Details
Published inGene Vol. 769; p. 145063
Main Authors Jing, Zhuang, Xi, Yang, Yin, Jin, Shuwen, Han
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 15.02.2021
Subjects
Animals
Colorectal cancer
colorectal neoplasms
Colorectal Neoplasms - genetics
genes
Humans
non-coding RNA
occurrence
piRNA
piwi-interacting RNA
piwiRNA
RNA, Small Interfering - physiology
signal transduction
piwi-interacting RNA
piwiRNA
Colorectal cancer
piRNA
Online AccessGet full text

Cover

More Information
Summary:Colorectal cancer (CRC) is one of the most common malignancies worldwide and a major cause of cancer-related deaths. Numerous studies have suggested that piwi-interacting RNAs (piRNAs), a new type of non-coding RNA (ncRNA), are closely related to the occurrence and development of cancer. piRNAs have been shown to regulate the occurrence of CRC by modulating multiple molecular signaling pathways. Here, the roles of piRNAs in CRC were reviewed to provide evidence for their potential as molecular targets for CRC.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
ObjectType-Review-3
content type line 23
ISSN:0378-1119
1879-0038
1879-0038
DOI:10.1016/j.gene.2020.145063