A NOVEL VARIANT OF STAPHYLOKINASE GENE FROM STAPHYLOCOCCUS AUREUS ATCC 29213

• Published in: Thrombosis research Vol. 87; no. 4; pp. 387 - 395
• Main Authors: Kim, Seung-Ho, Chun, Hong-Sung, Han, Moon Hi, Park, Na-Young, Suk, Kyoungho
• Format: Journal Article
• Language: English
• Published: New York, NY Elsevier Ltd 15.08.1997; Elsevier Science
• Subjects: Amino Acid Sequence; Bacteriology; Base Sequence; Biological and medical sciences; Blood. Blood coagulation. Reticuloendothelial system; Cloning, Molecular; DNA, Complementary - genetics; DNA, Complementary - isolation & purification; fibrinolysis; Fundamental and applied biological sciences. Psychology; Genes, Bacterial; Medical sciences; Metabolism. Enzymes; Metalloendopeptidases - genetics; Microbiology; Molecular Sequence Data; Pharmacology. Drug treatments; S. aureus; Sequence Alignment; Staphylococcus aureus - genetics; staphylokinase; fibrinolysis; staphylokinase; S. aureus; Enzyme; Gene product; Transferases; Genetic variant; In vitro; Biological activity; Gene; Kinase; Bacteria; Micrococcales; Micrococcaceae; Fibrinolytic; Staphylococcus aureus; Aminoacid sequence

The processes of hemostasis and thrombolysis are elegantly regulated in order to ensure normal functions of vascular system. A search for new plasminogen activators as thrombolytic agents has been carried out for the purpose of clinical applications to modulate thrombolytic processes. In the current...