Cisapride-induced long QT interval

A 2-month-old infant with gastroesophageal reflux was treated with cisapride. Bradycardia developed and an electrocardiogram revealed 2:1 atrioventricular conduction and a prolonged QT interval. After cessation of cisapride therapy, both the rhythm and the QT interval returned to normal. Prolonged Q...

Full description

Saved in:
Bibliographic Details
Published inThe Journal of pediatrics Vol. 128; no. 2; pp. 279 - 281
Main Authors Lewin, Mark B., Bryant, Randall M., Fenrich, Arnold L., Grifka, Ronald G.
Format Journal Article
LanguageEnglish
Published New York, NY Mosby, Inc 01.02.1996
Elsevier
Subjects
Adult
Age Factors
Biological and medical sciences
Bradycardia - chemically induced
Bradycardia - diagnosis
Cisapride
Drug toxicity and drugs side effects treatment
Electrocardiography
Female
Gastroesophageal Reflux - drug therapy
Humans
Infant
Long QT Syndrome - chemically induced
Long QT Syndrome - diagnosis
Medical sciences
Pharmacology. Drug treatments
Piperidines - administration & dosage
Piperidines - adverse effects
Piperidines - therapeutic use
Toxicity: cardiovascular system
QT c
Human
Gastroesophageal reflux
QT interval
Arrhythmia
Esophageal disease
Cardiovascular disease
Infant
Conduction disorder
Excitability disorder
Case study
Bradycardia
Chemotherapy
Treatment
Heart disease
Digestive diseases
Online AccessGet full text

Cover

More Information
Summary:A 2-month-old infant with gastroesophageal reflux was treated with cisapride. Bradycardia developed and an electrocardiogram revealed 2:1 atrioventricular conduction and a prolonged QT interval. After cessation of cisapride therapy, both the rhythm and the QT interval returned to normal. Prolonged QT interval during treatment with cisapride may occur in children as in adults. (J P EDIATR 1996;128:279-81)
ISSN:0022-3476
1097-6833
DOI:10.1016/S0022-3476(96)70409-2