Distribution and metabolism of hexadecylphosphocholine in mice

• Published in: Lipids Vol. 22; no. 11; pp. 925 - 926
• Main Authors: Breiser, A., Kim, D. ‐J., Fleer, E. A. M., Damenz, W., Drube, A., Berger, M., Nagel, G. A., Eibl, H., Unger, C.
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer‐Verlag 01.11.1987
• Subjects: Administration, Oral; Animals; Choline - analogs & derivatives; Female; Mice; Phosphorylcholine - administration & dosage; Phosphorylcholine - analogs & derivatives; Phosphorylcholine - pharmacokinetics; Tissue Distribution

Distribution and metabolic fate of radiolabeled hexadecylphosphocholine (He‐PC) has been studied in mice. It is demonstrated that He‐PC is well‐absorbed from the intestinal tract, intravenous (IV) and oral administration lead to similar distributions throughout the body, the highest accumulation of...