Identification of optimal combinations for empirical dual antimicrobial therapy of Pseudomonas aeruginosa infection: potential role of a Combination Antibiogram
To better determine the optimal combinations for empirical dual antimicrobial therapy of Pseudomonas aeruginosa infection, we evaluated the utility of a novel combination antibiogram. Although the combination antibiogram allowed modest fine-tuning of choices for dual antibiotic therapy, selections b...
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| Published in | Infection control and hospital epidemiology Vol. 27; no. 4; p. 413 |
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| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
01.04.2006
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| Subjects | |
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| Abstract | To better determine the optimal combinations for empirical dual antimicrobial therapy of Pseudomonas aeruginosa infection, we evaluated the utility of a novel combination antibiogram. Although the combination antibiogram allowed modest fine-tuning of choices for dual antibiotic therapy, selections based on the 2 antibiograms did not differ substantively. Drug combinations with the broadest coverage were consistently composed of an aminoglycoside and a beta-lactam. |
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| AbstractList | To better determine the optimal combinations for empirical dual antimicrobial therapy of Pseudomonas aeruginosa infection, we evaluated the utility of a novel combination antibiogram. Although the combination antibiogram allowed modest fine-tuning of choices for dual antibiotic therapy, selections based on the 2 antibiograms did not differ substantively. Drug combinations with the broadest coverage were consistently composed of an aminoglycoside and a beta-lactam. |
| Author | Fishman, Neil O Sheridan, Angela Mizuta, Mari Weiner, Mark G Lautenbach, Ebbing Linkin, Darren R Nachamkin, Irving |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/16622822$$D View this record in MEDLINE/PubMed |
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| References | 18624670 - Infect Control Hosp Epidemiol. 2008 Jul;29(7):678-9 |
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| SubjectTerms | Anti-Bacterial Agents - classification Anti-Bacterial Agents - pharmacology Anti-Bacterial Agents - therapeutic use Drug Resistance, Microbial Drug Therapy, Combination Hospitals, University Humans Microbial Sensitivity Tests Philadelphia Pseudomonas aeruginosa - drug effects Pseudomonas aeruginosa - isolation & purification Pseudomonas Infections - drug therapy |
| Title | Identification of optimal combinations for empirical dual antimicrobial therapy of Pseudomonas aeruginosa infection: potential role of a Combination Antibiogram |
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