Fluorescent nanoparticles as selective Cu(II) sensors

• Published in: Photochemical & photobiological sciences Vol. 5; no. 3; pp. 300 - 310
• Main Authors: Meallet-Renault, R, Herault, A, Vachon, JJ, Pansu, RB, Amigoni-Gerbier, S, Larpent, C
• Format: Journal Article
• Language: English
• Published: LONDON Springer Nature 01.03.2006; Springer
• Subjects: Biochemistry & Molecular Biology; Biophysics; Boron Compounds - chemical synthesis; Boron Compounds - chemistry; Chelating Agents - chemistry; Chemistry; Chemistry, Physical; Copper - chemistry; Energy Transfer; Fluorescence Polarization - methods; Fluorescent Dyes - chemistry; Heterocyclic Compounds - chemistry; Heterocyclic Compounds, 3-Ring - chemical synthesis; Heterocyclic Compounds, 3-Ring - chemistry; Life Sciences & Biomedicine; Nanostructures - chemistry; Physical Sciences; Science & Technology; Sensitivity and Specificity; Spectrometry, Fluorescence - methods; OXYGEN; FUNCTIONALIZED NANOPARTICLES; CHEMOSENSOR; DYES; NANOSENSOR; MICROEMULSIONS; SURFACE; POLYMERIZATION; ELECTRONIC-ENERGY TRANSFER; METAL-COMPLEXING NANOPARTICLES
• ISSN: 1474-905X; 1474-9092
• DOI: 10.1039/b513215k

Latex nanoparticles functionalized with cyclam (1,4,8,11- tetraazacyclotetradecane), a copper chelator, have been doped with a fluorescent dye 1 (BODIPY derivative:4,4-difluoro-8-(2',4',6'-trimethyl) phenyl2,6- diethyl-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene). The bulky, hydrophobic fluorophore 1 dissolves within the nanoparticles' polymer core up to a concentration of about 88.4 mu mol g(-1). At this concentration the fluorescence yield is about 0.80. Adding Cu2+ ions to the solution decreases the fluorescence because of the energy transfer between the dye and the violet copper cyclam complexes. The response is fast: 90% of the quenching occurs within 1 s. The Cu2+ detection threshold is of 1 nanomolar. No interferences were observed with zinc and nickel ions.