Localization of neuroendocrine tumours with [111In]DTPA-octreotide scintigraphy (Octreoscan) : A comparative study with CT and MR imaging

• Published in: QJM : An International Journal of Medicine Vol. 91; no. 4; pp. 295 - 301
• Main Authors: SHI, W, JOHNSTON, C. F, BUCHANAN, K. D, FERGUSON, W. R, LAIRD, J. D, CROTHERS, J. G, MCILRATH, E. M
• Format: Journal Article
• Language: English
• Published: Oxford Oxford University Press 01.04.1998
• Subjects: Adolescent; Adult; Aged; Biological and medical sciences; Carcinoid Tumor - diagnosis; Carcinoid Tumor - diagnostic imaging; Carcinoma, Medullary - diagnosis; Carcinoma, Medullary - diagnostic imaging; Child; Endocrine glands; Female; Humans; Indium Radioisotopes; Investigative techniques, diagnostic techniques (general aspects); Magnetic Resonance Imaging; Male; Medical sciences; Middle Aged; Neuroendocrine Tumors - diagnosis; Neuroendocrine Tumors - diagnostic imaging; Octreotide - analogs & derivatives; Pancreatic Neoplasms - diagnosis; Pancreatic Neoplasms - diagnostic imaging; Pentetic Acid - analogs & derivatives; Radiodiagnosis. Nmr imagery. Nmr spectrometry; Radionuclide Imaging; Radiopharmaceuticals; Sensitivity and Specificity; Thyroid Neoplasms - diagnosis; Thyroid Neoplasms - diagnostic imaging; Tomography, X-Ray Computed; Endocrinopathy; Human; Evaluation; Octreotide; Nuclear magnetic resonance imaging; Analog; Neurohypophyseal hormone; Medical imagery; Specific identification; Computerized axial tomography; Somatostatin; Diagnosis; Emission transmission scintigraphy; Neuroendocrine tumor; Comparative study

A wide variety of neuroendocrine tumours express somatostatin receptors, and can be visualized by radiolabelled somatostatin analogue scintigraphy. To investigate the value of [111In]-octreotide scintigraphy (Octreoscan), 48 patients (37 with proven carcinoid, pancreatic endocrine and medullary carc...