Naloxone in advanced cardiac life support: myth or reality?

In a prospective, randomized, placebo-controlled, double-blinded trial in a porcine model of cardiac arrest, Gervais and associates [13] found no improvement in the myocardial perfusion pressure or cerebral perfusion pressure after the administration of naloxone 10 mg/kg. [...]the addition of naloxo...

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Bibliographic Details
Published inThe American journal of emergency medicine Vol. 26; no. 8; pp. 902 - 903
Main Authors Mendoza-Davila, Natalia, MS, Varon, Joseph, MD
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.10.2008
Elsevier Limited
Subjects
Adrenergic Agonists - therapeutic use
Advanced Cardiac Life Support
Animals
Cardiopulmonary resuscitation
Clinical Trials as Topic
Confidence intervals
CPR
Drug Therapy, Combination
Emergency
Emergency medical care
Epinephrine - therapeutic use
Heart Arrest - drug therapy
Heart attacks
Humans
Naloxone - therapeutic use
Shock - drug therapy
Studies
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Summary:In a prospective, randomized, placebo-controlled, double-blinded trial in a porcine model of cardiac arrest, Gervais and associates [13] found no improvement in the myocardial perfusion pressure or cerebral perfusion pressure after the administration of naloxone 10 mg/kg. [...]the addition of naloxone had shorter resuscitation times.
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Editorial-2
ObjectType-Commentary-1
ISSN:0735-6757
1532-8171
DOI:10.1016/j.ajem.2008.05.016