Chemical inhibition of foamyvirus in primary baboon ( Papio cynocephalus) kidney cells

This report describes the conditions for the use of aluminum chloride (AlCl 3) in growth and maintenance media for the suppression or inhibition of simian foamyviruses (SFV) in primary baboon kidney (BAK) and rabbit kidney (RK) cell cultures. When RK cells were planted in medium containing AlCl 3, i...

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Published inJournal of virological methods Vol. 4; no. 4; pp. 199 - 207
Main Authors Weiss, S.A., Heberling, R.L., Kalter, S.S.
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.01.1982
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Summary:This report describes the conditions for the use of aluminum chloride (AlCl 3) in growth and maintenance media for the suppression or inhibition of simian foamyviruses (SFV) in primary baboon kidney (BAK) and rabbit kidney (RK) cell cultures. When RK cells were planted in medium containing AlCl 3, infected with SFV, and passaged, the growth of SFV was suppressed or inhibited by the presence of AlCl 3. With this method, BAK cells yielded higher viral titers after infection with various viruses, thus making these cells more suitable for virological applications.
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ISSN:0166-0934
1879-0984
DOI:10.1016/0166-0934(82)90066-0