Suppression of anaphylactic shock in sensitized guinea pigs by cytochalasin B
Twenty-three guinea pigs, presensitized with horse serum, were injected intracardially with 1ml of 1.5× 10 −4 M cytochalasin B in a 2.5% dimethyl sulfoxide solution, 1.5 h before being challenged with the serum. Eighteen of the guinea pigs (80%) survived. A single intracardiac injection of cytochala...
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Published in | Immunology letters Vol. 22; no. 3; pp. 193 - 194 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Netherlands
Elsevier B.V
01.09.1989
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Subjects | |
Online Access | Get full text |
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Summary: | Twenty-three guinea pigs, presensitized with horse serum, were injected intracardially with 1ml of 1.5× 10
−4 M cytochalasin B in a 2.5% dimethyl sulfoxide solution, 1.5 h before being challenged with the serum. Eighteen of the guinea pigs (80%) survived. A single intracardiac injection of cytochalasin B to the control group of guinea pigs at 1.5 h before administration of the allergen did not prevent their sensitization and death following challenge. |
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Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
ISSN: | 0165-2478 1879-0542 |
DOI: | 10.1016/0165-2478(89)90189-2 |