Tolvaptan Response in a Hyponatremic Newborn with Syndrome of Inappropriate Secretion of Antidiuretic Hormone

The use of tolvaptan to treat both euvolemic and hypervolemic hyponatremia has rapidly increased in recent years. However, data on its effects on children, especially newborns and infants, are limited. Here, we present a newborn who developed syndrome of inappropriate secretion of antidiuretic hormo...

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Bibliographic Details
Published inCase reports in pediatrics Vol. 2021; pp. 1 - 4
Main Authors Zeybek, Cengiz, Bozat, Ali Dinç, Calisici, Erhan, Bolat, Ahmet, Saygili Karagol, Belma
Format Journal Article
LanguageEnglish
Published New York Hindawi 12.05.2021
Hindawi Limited
Wiley
Subjects
Age
Case Report
Case reports
Drug dosages
Edema
Hematoma
Kidneys
Newborn babies
Patients
Pediatrics
Regression analysis
Sodium
Thyroid gland
Ultrasonic imaging
Urine
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Summary:The use of tolvaptan to treat both euvolemic and hypervolemic hyponatremia has rapidly increased in recent years. However, data on its effects on children, especially newborns and infants, are limited. Here, we present a newborn who developed syndrome of inappropriate secretion of antidiuretic hormone following an intracranial hematoma drainage operation who was unresponsive to conventional treatments. The infant was successfully treated with tolvaptan, a competitive inhibitor of the vasopressin V2 receptor.
Bibliography:Academic Editor: Carmelo Romeo
ISSN:2090-6803
2090-6811
DOI:10.1155/2021/9920817