Correction: The Cytokine Release Inhibitory Drug CRID3 Targets ASC Oligomerisation in the NLRP3 and AIM2 Inflammasomes

[...]subsequent analysis of the Amgen compound by liquid chromatography-mass spectrometry (LC-MS), tandem mass spectrometry (MS-MS) and NMR (nuclear magnetic resonance) (see files attached to this Correction) revealed that the compound is a different structure, namely 1-(5-carboxy-2-{3-[4-(3-yclohex...

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Bibliographic Details
Published inPloS one Vol. 8; no. 2
Main Authors Coll, Rebecca C., O'Neill, Luke A. J.
Format Journal Article
LanguageEnglish
Published San Francisco Public Library of Science 27.02.2013
Public Library of Science (PLoS)
Subjects
Annotations
Carboxylic acids
Chromatography
Cytokines
Ions
Liquid chromatography
Magnetic resonance
Mass spectrometry
NMR
Nuclear magnetic resonance
Scientific imaging
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Summary:[...]subsequent analysis of the Amgen compound by liquid chromatography-mass spectrometry (LC-MS), tandem mass spectrometry (MS-MS) and NMR (nuclear magnetic resonance) (see files attached to this Correction) revealed that the compound is a different structure, namely 1-(5-carboxy-2-{3-[4-(3-yclohexylpropoxy)phenyl]propoxy}benzoyl)piperidine-4-carboxylic acid as described by Härter, M. et al. The mass spectrometry and NMR analysis undertaken to characterize the compound, and which are included in this Correction, were carried out by Dr. Avril Robertson and Dr. Mark Butler in Prof. Matt Cooper's laboratory at the Institute for Molecular Bioscience, The University of Queensland, Australia.
Bibliography:correction
ISSN:1932-6203
1932-6203
DOI:10.1371/annotation/9f221489-155d-4978-a36d-30c51853e438